The Cell Culture Module has two major functions: (1) to help investigators use cultures effectively in their research, and (2) to provide a mechanism for optimum sharing of ocular specimens from human and animal eyes. To fulfill the first function, the Module: (a) serves as a repository for several types of cultured ocular cells and cell lines, (b) provides a centralized facility with shared-use equipment for culture maintenance for those who lack culture facilities in their own labs, (c) provides shared-use instruments (such as inverted phase and fluorescence photomicroscopes) for investigators who have basic culture facilities to avoid duplication of all equipment, and (d) assists investigators in using in vitro models for their work including bringing culture methods into their own labs by training laboratory personnel in culture techniques. The availability of this Module also improves the economy of our lab operations since commonly-used culture supplies can be purchased in bulk.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
4P30EY001931-40
Application #
9096813
Study Section
Special Emphasis Panel (ZEY1)
Project Start
Project End
Budget Start
2016-07-01
Budget End
2017-06-30
Support Year
40
Fiscal Year
2016
Total Cost
Indirect Cost
Name
Medical College of Wisconsin
Department
Type
DUNS #
937639060
City
Milwaukee
State
WI
Country
United States
Zip Code
53226
Reid, Christopher A; Nettesheim, Emily R; Connor, Thomas B et al. (2018) Development of an inducible anti-VEGF rAAV gene therapy strategy for the treatment of wet AMD. Sci Rep 8:11763
Zhang, Hanmeng; Mu, Lianwei; Wang, Dandan et al. (2018) Uncovering a critical period of synaptic imbalance during postnatal development of the rat visual cortex: role of brain-derived neurotrophic factor. J Physiol 596:4511-4536
Lewis, Tylor R; Kundinger, Sean R; Link, Brian A et al. (2018) Kif17 phosphorylation regulates photoreceptor outer segment turnover. BMC Cell Biol 19:25
Huckenpahler, Alison; Wilk, Melissa; Link, Brian et al. (2018) Repeatability and Reproducibility of In Vivo Cone Density Measurements in the Adult Zebrafish Retina. Adv Exp Med Biol 1074:151-156
Lewis, Tylor R; Zareba, Mariusz; Link, Brian A et al. (2018) Cone myoid elongation involves unidirectional microtubule movement mediated by dynein-1. Mol Biol Cell 29:180-190
Lee, Daniel J; Woertz, Erica N; Visotcky, Alexis et al. (2018) The Henle Fiber Layer in Albinism: Comparison to Normal and Relationship to Outer Nuclear Layer Thickness and Foveal Cone Density. Invest Ophthalmol Vis Sci 59:5336-5348
Linderman, Rachel E; Muthiah, Manickam N; Omoba, Sarah B et al. (2018) Variability of Foveal Avascular Zone Metrics Derived From Optical Coherence Tomography Angiography Images. Transl Vis Sci Technol 7:20
Vogel, Ryan N; Strampe, Margaret; Fagbemi, Oladipo E et al. (2018) Foveal Development in Infants Treated with Bevacizumab or Laser Photocoagulation for Retinopathy of Prematurity. Ophthalmology 125:444-452
Warren, Clinton C; Young, Jonathon B; Goldberg, Mara R et al. (2018) Findings in Persistent Retinopathy of Prematurity. Ophthalmic Surg Lasers Imaging Retina 49:497-503
Strampe, Margaret R; Huckenpahler, Alison L; Higgins, Brian P et al. (2018) Intraobserver Repeatability and Interobserver Reproducibility of Ellipsoid Zone Measurements in Retinitis Pigmentosa. Transl Vis Sci Technol 7:13

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