This NEI P30 award provides ongoing and stable funding for four high quality and productive vision research service Modules: Instrument Design, Research Computer Programming, Biostatistics and Clinical Research, and Biological Imaging. These Modules are run by an exceptionally talented staff that has from 7 to 20 years of experience in our Core Center for Vision Research. The Modules provide needed research services to the present group of 23 Core Center vision scientists who come from 5 departments of the University of Houston (Chemistry, Physics, Electrical Engineering, and Clinical Sciences and Vision Sciences in Optometry). These Core vision scientists have diverse training and research interests;they collaborate effectively with one another, as well as with more than 100 other vision researchers at this University or other institutions. Together, our 23 Core Center investigators have 14 qualifying NEI-funded grants. The College of Optometry and University of Houston provide considerable additional commitments in support of vision research. During the past 5 years of P30 funding at this University, the Core Center has created a favorable vision research environment that has contributed directly to 186 published papers and culminated in the recruitment of 5 new vision investigators, 2 of whom currently have NEI funding. The Core Center also was crucial to the success of two clinicians (ODs) in obtaining new NEI funding for mentored clinician scientists. These accomplishments reflect our Core Center's previous and current aims that focus on stable funding, quality research services, collaborative and innovative basic, clinical and translational research, new vision researchers, and new projects converting into NIH and NEI support. Especially emphasized in the coming 5 years will be innovative research basic, clinical and translational research and recruitment of vision researchers to fill our current open positions, as well as other positions in the future. The Core Center for Vision Research in the College of Optometry at the University of Houston improves visual health by supporting investigators doing basic, clinical and translational research on vision and vision disorders.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY007551-24
Application #
8068786
Study Section
Special Emphasis Panel (ZEY1-VSN (04))
Program Officer
Liberman, Ellen S
Project Start
1997-03-01
Project End
2013-04-30
Budget Start
2011-05-01
Budget End
2012-04-30
Support Year
24
Fiscal Year
2011
Total Cost
$602,265
Indirect Cost
Name
University of Houston
Department
Type
Schools of Optometry/Ophthalmol
DUNS #
036837920
City
Houston
State
TX
Country
United States
Zip Code
77204
Rodarte, Elsa M; Ramos, Marco A; Davalos, Alfredo J et al. (2018) Munc13 proteins control regulated exocytosis in mast cells. J Biol Chem 293:345-358
Takahata, Toru; Patel, Nimesh B; Balaram, Pooja et al. (2018) Long-term histological changes in the macaque primary visual cortex and the lateral geniculate nucleus after monocular deprivation produced by early restricted retinal lesions and diffuser induced form deprivation. J Comp Neurol 526:2955-2972
Lentsch, Matthew J; Marsack, Jason D; Anderson, Heather A (2018) Objective measurement of spectacle wear with a temperature sensor data logger. Ophthalmic Physiol Opt 38:37-47
Skidmore, Kelsea V; Walker, Maria K; Marsack, Jason D et al. (2018) A measure of tear inflow in habitual scleral lens wearers with and without midday fogging. Cont Lens Anterior Eye :
Hung, Li-Fang; Arumugam, Baskar; She, Zhihui et al. (2018) Narrow-band, long-wavelength lighting promotes hyperopia and retards vision-induced myopia in infant rhesus monkeys. Exp Eye Res 176:147-160
Roberts, Tawna L; Manny, Ruth E; Benoit, Julia S et al. (2018) Impact of Cognitive Demand during Sustained Near Tasks in Children and Adults. Optom Vis Sci 95:223-233
Patel, Nimesh; McAllister, Faith; Pardon, Laura et al. (2018) The effects of graded intraocular pressure challenge on the optic nerve head. Exp Eye Res 169:79-90
Hung, Li-Fang; Arumugam, Baskar; Ostrin, Lisa et al. (2018) The Adenosine Receptor Antagonist, 7-Methylxanthine, Alters Emmetropizing Responses in Infant Macaques. Invest Ophthalmol Vis Sci 59:472-486
Gutierrez, Berenice A; Chavez, Miguel A; Rodarte, Alejandro I et al. (2018) Munc18-2, but not Munc18-1 or Munc18-3, controls compound and single-vesicle-regulated exocytosis in mast cells. J Biol Chem 293:7148-7159
Davis, Joshua T; Foster, William J (2018) Substrate Stiffness Influences the Time Dependence of CTGF Protein Expression in Müller Cells. Int Physiol J 1:1

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