The overall goal of the proposed Vision Core is to enhance vision research at Harvard by providing vision scientists with resources and facilities that could not be supported by individual laboratories. A further objective of the Vision Core is to provide a focus that will encourage collaborations between vision scientists and encourage other researchers to do research on vision and the eye. The Vision Core will provide continuing support for four existing core modules that have been serving the needs of the vision research community during the current funding period. A neural imaging module provides resources to support experiments using a wide variety of state-of-the-art imaging techniques, including in vivo two-photon microscopy, functional imaging and quantitative microscopy. A machine shop module provides services for designing and manufacturing special equipment that cannot be obtained commercially. A laboratory computer service module provides assistance in interfacing laboratory equipment and in designing and developing code to support experiments. Finally, an electronics module provides services for designing and constructing specialized electronic circuits and devices.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY012196-15
Application #
8228065
Study Section
Special Emphasis Panel (ZEY1-VSN (04))
Program Officer
Liberman, Ellen S
Project Start
1998-03-01
Project End
2013-06-30
Budget Start
2012-03-01
Budget End
2013-06-30
Support Year
15
Fiscal Year
2012
Total Cost
$774,084
Indirect Cost
$317,397
Name
Harvard University
Department
Biology
Type
Schools of Medicine
DUNS #
047006379
City
Boston
State
MA
Country
United States
Zip Code
02115
Chen, Bo; Li, Yi; Yu, Bin et al. (2018) Reactivation of Dormant Relay Pathways in Injured Spinal Cord by KCC2 Manipulations. Cell 174:1599
Xu, Jie; Bartolome, Christopher L; Low, Cho Shing et al. (2018) Genetic identification of leptin neural circuits in energy and glucose homeostases. Nature 556:505-509
Martínez-François, Juan Ramón; Fernández-Agüera, María Carmen; Nathwani, Nidhi et al. (2018) BAD and KATP channels regulate neuron excitability and epileptiform activity. Elife 7:
Liu, Yuanyuan; Latremoliere, Alban; Li, Xinjian et al. (2018) Touch and tactile neuropathic pain sensitivity are set by corticospinal projections. Nature 561:547-550
Chen, Bo; Li, Yi; Yu, Bin et al. (2018) Reactivation of Dormant Relay Pathways in Injured Spinal Cord by KCC2 Manipulations. Cell 174:521-535.e13
Liu, Jinyue; Reggiani, Jasmine D S; Laboulaye, Mallory A et al. (2018) Tbr1 instructs laminar patterning of retinal ganglion cell dendrites. Nat Neurosci 21:659-670
Todd, Nick; Zhang, Yongzhi; Arcaro, Michael et al. (2018) Focused ultrasound induced opening of the blood-brain barrier disrupts inter-hemispheric resting state functional connectivity in the rat brain. Neuroimage 178:414-422
Liang, Liang; Fratzl, Alex; Goldey, Glenn et al. (2018) A Fine-Scale Functional Logic to Convergence from Retina to Thalamus. Cell 173:1343-1355.e24
Markowitz, Jeffrey E; Gillis, Winthrop F; Beron, Celia C et al. (2018) The Striatum Organizes 3D Behavior via Moment-to-Moment Action Selection. Cell 174:44-58.e17
Crake, Calum; Brinker, Spencer T; Coviello, Christian M et al. (2018) A dual-mode hemispherical sparse array for 3D passive acoustic mapping and skull localization within a clinical MRI guided focused ultrasound device. Phys Med Biol 63:065008

Showing the most recent 10 out of 131 publications