Abstract

The Assessment Core is conceptually and methodologically central to the CRC. At the conceptual level the work involves identifying key psychopathological aspects of schizophrenia for investigation and the development of approaches to experimental design issues. At the methodological level is the implementation of reliable procedures for classifying and measuring psychopathology. The Assessment Core is designed: 1) to ensure that index assessments are collected on all patients entering CRC protocols; 2) to provide standard clinical, neurobehavioral, social competence, and family instruments for use in protocols; 3) to provide common training in the use of these instruments; and 4) to conduct ongoing reliability exercises, when applicable, for these instruments. The Assessment and Data Management Cores personnel meet monthly as a work group to ensure that the tasks of the two Cores are accomplished.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Center Core Grants (P30)
Project #
5P30MH040279-16
Application #
6660535
Study Section
Project Start
2002-09-01
Project End
2003-08-31
Budget Start
Budget End
Support Year
16
Fiscal Year
2002
Total Cost
$266,631
Indirect Cost

  Institution

Name
University of Maryland Baltimore
Department
Type
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201

  Publications

Warren, Kimberly R; Ball, M Patricia; Feldman, Stephanie et al. (2011) Exercise program adherence using a 5-kilometer (5K) event as an achievable goal in people with schizophrenia. Biol Res Nurs 13:383-90
Gao, Xue-Min; Elmer, Gregory I; Adams-Huet, Beverley et al. (2009) Social memory in mice: disruption with an NMDA antagonist and attenuation with antipsychotic drugs. Pharmacol Biochem Behav 92:236-42
Kelly, Deanna L; Wehring, Heidi J; Linthicum, Jared et al. (2009) Cardiac-related findings at autopsy in people with severe mental illness treated with clozapine or risperidone. Schizophr Res 107:134-8
Lahti, Adrienne C; Weiler, Martin A; Holcomb, Henry H et al. (2009) Modulation of limbic circuitry predicts treatment response to antipsychotic medication: a functional imaging study in schizophrenia. Neuropsychopharmacology 34:2675-90
Lahti, Adrienne C; Weiler, Martin A; Holcomb, Henry H et al. (2006) Correlations between rCBF and symptoms in two independent cohorts of drug-free patients with schizophrenia. Neuropsychopharmacology 31:221-30
Lahti, Adrienne C; Weiler, Martin A; Medoff, Deborah R et al. (2005) Functional effects of single dose first- and second-generation antipsychotic administration in subjects with schizophrenia. Psychiatry Res 139:19-30
McMahon, Robert P; Arndt, Stephan; Conley, Robert R (2005) More powerful two-sample tests for differences in repeated measures of adverse effects in psychiatric trials when only some patients may be at risk. Stat Med 24:11-21
Wilk, Christopher M; Gold, James M; Humber, Kathy et al. (2004) Brief cognitive assessment in schizophrenia: normative data for the Repeatable Battery for the Assessment of Neuropsychological Status. Schizophr Res 70:175-86
Lahti, Adrienne C; Holcomb, Henry H; Weiler, Martin A et al. (2004) Clozapine but not haloperidol Re-establishes normal task-activated rCBF patterns in schizophrenia within the anterior cingulate cortex. Neuropsychopharmacology 29:171-8
Lahti, Adrienne C; Holcomb, Henry H; Weiler, Martin A et al. (2003) Functional effects of antipsychotic drugs: comparing clozapine with haloperidol. Biol Psychiatry 53:601-8

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