The goal of the PHPP Core is to maximize the impact of HIV Center efficacious interventions by supporting research on the translation, adaptation, and adoption of scientifically tested prevention and treatment interventions into community-based delivery systems and other public health settings by partnering with policy makers, service system organizers, and ethicists. Since the beginning of the HIV epidemic, scientists have developed evidence-based interventions for HIV prevention, earlier identification of HIV cases, timely engagement and retention in care, and adherence to antiretroviral therapy (ART), Typically, advances emerge from randomized controlled trials, however, widespread adoption and demonstrable population-based health improvement has proved challenging. Interventions developed in academic isolation often fail to address real-world constraints - insufficient resources and workforce capacity;fragmented funding and policies;and tensions among recipients, providers, policy makers, and researchers [1,2], In addition, ethical dilemmas and lagging policy hinder timely adoption of evidence-based interventions, and the changing epidemic poses new challenges to front-line clinicians that academic researchers are slow to address. In light of the expected rapid advances in biobehavioral prevention and treatment approaches likely to emerge as the epidemic over the next five years, the HIV Center has chosen to make translational research and implementation science a high priority.
We aim to optimize the scale-up of our evidence-based interventions into practice settings and the use of evidence to inform health care policy and service delivery organization [3-5]. The PHPP Core has evolved from two current HIV Center cores, the Global Community Core (GCC) and Ethics and Policy Core. This new Core will build capacity in translational research and implementation science, provide sophisticated ethics and human rights consultation, and unite end users, policy-makers, delivery-organization leadership, and researchers in an ongoing partnership to address implementation challenges. The PHPP Core will specifically aim to close the gaps among science, policy, and HIV prevention and care services.
|Balán, Iván C; Giguere, Rebecca; Brown 3rd, William et al. (2018) Brief Participant-Centered Convergence Interviews Integrate Self-Reports, Product Returns, and Pharmacokinetic Results to Improve Adherence Measurement in MTN-017. AIDS Behav 22:986-995|
|Parcesepe, Angela M; Tymejczyk, Olga; Remien, Robert et al. (2018) Psychological distress, health and treatment-related factors among individuals initiating ART in Oromia, Ethiopia. AIDS Care 30:338-342|
|Iribarren, Sarah J; Ghazzawi, Alhasan; Sheinfil, Alan Z et al. (2018) Mixed-Method Evaluation of Social Media-Based Tools and Traditional Strategies to Recruit High-Risk and Hard-to-Reach Populations into an HIV Prevention Intervention Study. AIDS Behav 22:347-357|
|Barnes, David M; Des Jarlais, Don C; Wolff, Margaret et al. (2018) A qualitative study of persons who inject drugs but who have never helped others with first injections: how their views on helping contrast with the views of persons who have helped with first injections, and implications for interventions. Harm Reduct J 15:43|
|Masvawure, Tsitsi B; Mantell, Joanne E; Tocco, Jack Ume et al. (2018) Intentional and Unintentional Condom Breakage and Slippage in the Sexual Interactions of Female and Male Sex Workers and Clients in Mombasa, Kenya. AIDS Behav 22:637-648|
|Zhang, Yinfeng; Fogel, Jessica M; Guo, Xu et al. (2018) Antiretroviral drug use and HIV drug resistance among MSM and transgender women in sub-Saharan Africa. AIDS 32:1301-1306|
|Dawson, Liza; Strathdee, Steffanie A; London, Alex John et al. (2018) Addressing ethical challenges in HIV prevention research with people who inject drugs. J Med Ethics 44:149-158|
|Strauss, Michael; George, Gavin; Lansdell, Emma et al. (2018) HIV testing preferences among long distance truck drivers in Kenya: a discrete choice experiment. AIDS Care 30:72-80|
|Carballo-Diéguez, Alex; Lentz, Cody; Giguere, Rebecca et al. (2018) Rectal Douching Associated with Receptive Anal Intercourse: A Literature Review. AIDS Behav 22:1288-1294|
|Weintraub, Amy; Mantell, Joanne E; Holt, Kelsey et al. (2018) 'These people who dig roots in the forests cannot treat HIV': Women and men in Durban, South Africa, reflect on traditional medicine and antiretroviral drugs. Glob Public Health 13:115-127|
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