The Center for HIV Identification, Prevention, and Treatment Services (CHIPTS) is a collaboration of leading scientists from UCLA, Charles R. Drew University, Friends Research Institute, and RAND Corporation. CHIPTS' research agenda incorporates advances in HIV prevention science using combination antiretroviral therapy for those living with HIV and prophylactic antiretrovirals (ARVs) for high-risk HIV-negative individuals. Yet in key populations (e.g., young MSM of color, transgender, homeless, incarcerated, African American women), especially those with concurrent substance use and mental health disorders, barriers prevent access and adherence required to benefit from ARVs. CHIPTS will bridge these gaps with a plan to promote research, dissemination and training on treatment as prevention (TasP) in HIV-positive individuals and HIV prevention that integrates ARVs for high-risk, HIV-negative individuals (pre-exposure prophylaxis, PrEP), with emphasis on those with substance use and mental health disorders. CHIPTS has three specific aims. (1) SCIENCE: To promote novel, high impact and transformational research to eliminate barriers and to increase uptake, adherence, and persistence across the HIV prevention, care and policy continua. We study behavioral, biomedical, technological and structural approaches at individual, family, community, and policy impact levels that will stop new HIV infections, particularly in key populations. (2) NETWORKING: To sponsor meetings and provide venues for collaboration among scientists, providers, insurers, policy makers and stakeholders to accelerate uptake of high impact HIV prevention. (3) CAPACITY BUILDING: To mentor and train researchers, policy makers, providers, community leaders and staff members in health, criminal justice, social service, and administrative systems to reach HIV prevention goals for 90-90-90 by 2020. Our efforts are conducted domestically and globally. CHIPTS is comprised of five Cores. (1) Administrative Core leads CHIPTS interdisciplinary team, convenes center meetings and coordinates science, networking and capacity building agendas at local, state, national, and international levels. It ensures financial and scientific integrity, leads strategic planning and promotes a Global HIV Prevention Strategies Program. (2) Development Core invests in innovative, early stage research, supports emerging investigators and promotes dissemination events. (3) Combination Prevention Core promotes research on combination behavioral, biomedical, technological and structural interventions to reduce HIV incidence and to improve viral suppression, especially in key populations and those with substance use and mental health disorders. (4) Methods Core guides innovation and impact in measurement, statistical methods, and implementation science, focusing on factors presented by those with substance use and mental health disorders. (5) Policy Impact Core optimizes public health impact and science implementation by providing evidence on policy options to guide HIV prevention policy.

Public Health Relevance

Los Angeles has the second highest number of AIDS cases nationally and has one of the most ethnically diverse epidemics. Exciting developments in HIV prevention science have shifted the fight against new HIV infections from a lack of available effective interventions to a lack of will. The UCLA Center for HIV Identification, Prevention, and Treatment Services (CHIPTS) mobilizes world class leaders in the areas of science, networking and capacity building to lead the HIV prevention agenda both domestically and internationally.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Center Core Grants (P30)
Project #
5P30MH058107-24
Application #
9864087
Study Section
Special Emphasis Panel (ZMH1)
Program Officer
Gordon, Christopher M
Project Start
1997-09-30
Project End
2022-01-31
Budget Start
2020-02-01
Budget End
2021-01-31
Support Year
24
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Family Medicine
Type
Schools of Medicine
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Ojikutu, Bisola O; Srinivasan, Sumeeta; Bogart, Laura M et al. (2018) Mass incarceration and the impact of prison release on HIV diagnoses in the US South. PLoS One 13:e0198258
Garcia, Jonathan; Perez-Brumer, Amaya G; Cabello, Robinson et al. (2018) ""And Then Break the Cliché"": Understanding and Addressing HIV Vulnerability Through Development of an HIV Prevention Telenovela with Men Who Have Sex with Men and Transwomen in Lima, Peru. Arch Sex Behav 47:1995-2005
Daniels, Joseph; Marlin, Robert; Medline, Alex et al. (2018) Getting HIV Self-Test Kits into the Home for Young African American MSM in Los Angeles: A Qualitative Report. J Assoc Nurses AIDS Care 29:115-119
Harawa, Nina T; Brewer, Russell; Buckman, Victoria et al. (2018) HIV, Sexually Transmitted Infection, and Substance Use Continuum of Care Interventions Among Criminal Justice-Involved Black Men Who Have Sex With Men: A Systematic Review. Am J Public Health 108:e1-e9
Bogart, Laura M; Mosepele, Mosepele; Phaladze, Nthabiseng et al. (2018) A Social Network Analysis of HIV Treatment Partners and Patient Viral Suppression in Botswana. J Acquir Immune Defic Syndr 78:183-192
Beymer, Matthew R; Holloway, Ian W; Grov, Christian (2018) Comparing Self-Reported Demographic and Sexual Behavioral Factors Among Men Who Have Sex with Men Recruited Through Mechanical Turk, Qualtrics, and a HIV/STI Clinic-Based Sample: Implications for Researchers and Providers. Arch Sex Behav 47:133-142
Li, Michael J; Okafor, Chukwuemeka N; Gorbach, Pamina M et al. (2018) Intersecting burdens: Homophobic victimization, unstable housing, and methamphetamine use in a cohort of men of color who have sex with men. Drug Alcohol Depend 192:179-185
Ojikutu, Bisola O; Bogart, Laura M; Higgins-Biddle, Molly et al. (2018) Facilitators and Barriers to Pre-Exposure Prophylaxis (PrEP) Use Among Black Individuals in the United States: Results from the National Survey on HIV in the Black Community (NSHBC). AIDS Behav 22:3576-3587
Reback, Cathy J; Fletcher, Jesse B (2018) Elevated HIV and STI Prevalence and Incidence Among Methamphetamine-Using Men Who Have Sex With Men in Los Angeles County. AIDS Educ Prev 30:350-356
Kojima, Noah; Klausner, Jeffrey D (2018) An Update on the Global Epidemiology of Syphilis. Curr Epidemiol Rep 5:24-38

Showing the most recent 10 out of 715 publications