The overall goal of the Administrative core is to ensure the effective and efficient operation of Xenbase - a multi-PI resource with two performance sites.
The specific aims of the Admin core are to:
Aim 1 : To provide the administrative and organizational infrastructure necessary to implement our multi-PI plan and to maintain effective operations.
Aim 2 : To promote coordination and communication between the Development and Curation teams, and to facilitate integration of the different components of the project.
Aim 3 : To provide mechanisms for oversight and reporting to a) the Xenopus community, b) the External Advisory Board (EAB) and c) the NIH.
Aim 4 : To facilitate interactions between the Xenbase leadership and the leadership of other Model Organism databases (MODs), Stock Centers, and external resources such as NCBI, UniProtKB and the JGI.

Public Health Relevance

The Administrative Core provides the infrastructure and services to implement the multi- PI and multi-site plan. It coordinates communications, integrates the activities of the different components and manages reporting to the NIH and EAB.

National Institute of Health (NIH)
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Biotechnology Resource Grants (P41)
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Special Emphasis Panel (ZHD1)
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Cincinnati Children's Hospital Medical Center
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Patrushev, Ilya; James-Zorn, Christina; Ciau-Uitz, Aldo et al. (2018) New methods for computational decomposition of whole-mount in situ images enable effective curation of a large, highly redundant collection of Xenopus images. PLoS Comput Biol 14:e1006077
Karimi, Kamran; Wuitchik, Daniel M; Oldach, Matthew J et al. (2018) Distinguishing Species Using GC Contents in Mixed DNA or RNA Sequences. Evol Bioinform Online 14:1176934318788866
Karimi, Kamran; Fortriede, Joshua D; Lotay, Vaneet S et al. (2018) Xenbase: a genomic, epigenomic and transcriptomic model organism database. Nucleic Acids Res 46:D861-D868
James-Zorn, Christina; Ponferrada, Virgilio; Fisher, Malcolm E et al. (2018) Navigating Xenbase: An Integrated Xenopus Genomics and Gene Expression Database. Methods Mol Biol 1757:251-305
Vize, Peter D; Zorn, Aaron M (2017) Xenopus genomic data and browser resources. Dev Biol 426:194-199
Session, Adam M; Uno, Yoshinobu; Kwon, Taejoon et al. (2016) Genome evolution in the allotetraploid frog Xenopus laevis. Nature 538:336-343
Deans, Andrew R; Lewis, Suzanna E; Huala, Eva et al. (2015) Finding our way through phenotypes. PLoS Biol 13:e1002033
Vize, Peter D; Liu, Yu; Karimi, Kamran (2015) Database and Informatic Challenges in Representing Both Diploid and Tetraploid Xenopus Species in Xenbase. Cytogenet Genome Res 145:278-82
Grant, Ian M; Balcha, Dawit; Hao, Tong et al. (2015) The Xenopus ORFeome: A resource that enables functional genomics. Dev Biol 408:345-57
James-Zorn, Christina; Ponferrada, Virgillio G; Burns, Kevin A et al. (2015) Xenbase: Core features, data acquisition, and data processing. Genesis 53:486-97

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