This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Cognitive hallmarks of Williams syndrome (WS) include severe visuospatial deficits, and relative strengths in face and object processing (Meyer-Lindenberg et al., 2006). Functional neuroimaging data has indicated anomalous functional connectivity of the dorsal stream in WS.
Specific Aims : To investigate whether WS has aberrant connectivity of dorsal stream white matter tracts which may link between genetic and visuospatial abnormalities in WS. Methods: We used diffusion tensor imaging to examine white matter integrity in the dorsal and ventral streams among individuals with Williams syndrome (WS) compared to two control groups (typically developing and developmentally delayed) and using three separate analysis methods (whole brain, region of interest, and fiber tractography).

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
2P41RR009784-16
Application #
8169866
Study Section
Special Emphasis Panel (ZRG1-SBIB-U (40))
Project Start
2010-07-01
Project End
2011-03-31
Budget Start
2010-07-01
Budget End
2011-03-31
Support Year
16
Fiscal Year
2010
Total Cost
$12,333
Indirect Cost
Name
Stanford University
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94305
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