The Administrative Core will provide support for the research, training, community engagement, and information and technology transfer in this Program Project. Core leadership is provided by the Program Director/Principal Investigator, Dr. Norbert Kaminski. The Core will be located within the offices of the Center for Integrative Toxicology at Michigan State University, a unit coordinating campus-wide multidisciplinary activities in environmental and molecular toxicology. The Principal Investigator is Director of the Center. Staff for the Administrative Core includes a part-time accountant/administrator and a part-time secretary. The PD/PI will provide administrative and scientific leadership of the research program with input from an Internal and an External Advisory Committee. The Core will organize and support regularly scheduled meetings and video-conferencing for exchange of research and administrative information among the entire research group. It will prepare progress reports and other information that is required by the NIEHS Superfund Research Program (SRP) administration. Fiscal responsibilities attributed to the Core will include management and dissemination of funds to research projects and cores, monitoring of expenditures, and communication and reporting as required by NIEHS fiscal administration personnel. The Core will take leadership in and organize activities involving communication with government officials and personnel regarding the research program. Communications required for technology transfer will be enhanced through Core activities, including updating of website information concerning research progress. A Pilot Project Program providing non-NIH funds principally from institutional support will be used for initiation of new research projects will also be administered by the Core.

Public Health Relevance

The Administrative Core will provide support for the research, training, community engagement, and information and technology transfer in this Center Program. The Core will take leadership for regular communication with Center investigators and NIEHS for exchange of information, prepare progress reports, fiscal responsibility, technology transfer and communication with stakeholders in government, academia and industry regarding the research program.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
5P42ES004911-26
Application #
9257390
Study Section
Special Emphasis Panel (ZES1-LWJ-D)
Project Start
Project End
2019-03-31
Budget Start
2017-04-01
Budget End
2018-03-31
Support Year
26
Fiscal Year
2017
Total Cost
$117,028
Indirect Cost
$48,207
Name
Michigan State University
Department
Type
Domestic Higher Education
DUNS #
193247145
City
East Lansing
State
MI
Country
United States
Zip Code
48824
Nault, Rance; Doskey, Claire M; Fader, Kelly A et al. (2018) Comparison of Hepatic NRF2 and Aryl Hydrocarbon Receptor Binding in 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Treated Mice Demonstrates NRF2-Independent PKM2 Induction. Mol Pharmacol 94:876-884
Dornbos, Peter; LaPres, John J (2018) Incorporating population-level genetic variability within laboratory models in toxicology: From the individual to the population. Toxicology 395:1-8
Zhang, Shuai; Liu, Qinfu; Gao, Feng et al. (2018) Interfacial Structure and Interaction of Kaolinite Intercalated with N-methylformamide Insight from Molecular Dynamics Modeling. Appl Clay Sci 158:204-210
Fader, Kelly A; Nault, Rance; Raehtz, Sandi et al. (2018) 2,3,7,8-Tetrachlorodibenzo-p-dioxin dose-dependently increases bone mass and decreases marrow adiposity in juvenile mice. Toxicol Appl Pharmacol 348:85-98
Zhang, Shuai; Liu, Qinfu; Cheng, Hongfei et al. (2018) Mechanism Responsible for Intercalation of Dimethyl Sulfoxide in Kaolinite: Molecular Dynamics Simulations. Appl Clay Sci 151:46-53
Zhang, Qiang; Li, Jin; Middleton, Alistair et al. (2018) Bridging the Data Gap From in vitro Toxicity Testing to Chemical Safety Assessment Through Computational Modeling. Front Public Health 6:261
Fader, K A; Nault, R; Kirby, M P et al. (2018) Corrigendum to ""Convergence of hepcidin deficiency, systemic iron overloading, heme accumulation, and REV-ERB?/? activation in aryl hydrocarbon receptor-elicited hepatotoxicity"" [Toxicol. Appl. Pharmacol. 321 (2017) 1-17]. Toxicol Appl Pharmacol 344:74
Konganti, Kranti; Ehrlich, Andre; Rusyn, Ivan et al. (2018) gQTL: A Web Application for QTL Analysis Using the Collaborative Cross Mouse Genetic Reference Population. G3 (Bethesda) 8:2559-2562
Zhang, Shuai; Liu, Qinfu; Gao, Feng et al. (2018) Molecular Dynamics Simulation of Basal Spacing, Energetics, and Structure Evolution of a Kaolinite-Formamide Intercalation Complex and Their Interfacial Interaction. J Phys Chem C Nanomater Interfaces 122:3341-3349
Stedtfeld, Robert D; Chai, Benli; Crawford, Robert B et al. (2017) Modulatory Influence of Segmented Filamentous Bacteria on Transcriptomic Response of Gnotobiotic Mice Exposed to TCDD. Front Microbiol 8:1708

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