The Research Translation Core (RTC) of the METALS Center will utilize a unique network built over nearly four decades to facilitate the multidirectional translation of information among our researchers and trainees and to impacted Native American communities, local, regional and national governmental partners, other SRP researchers and important end-users to address real and immediate concerns related to mixed metals exposures from abandoned uranium mining sites. Our hypothesis is that increased multidirectional translation and communication supports more informed prevention, research, and policy decisions. The RTC aims (1) establish research translation forums among UNM METALS researchers, trainees, and cores to identify and translate research products within METALS and to other SRP programs; (2) expand our communications interface across a network of governmental agencies at the tribal, state, and national levels with shared information needs on the health effects and risk reduction strategies for metals mixtures exposures; (3) develop and apply unique multi-directional research translation frameworks to provide timely and understandable information to community partners and other important end users to enabling them to engage in setting policy and future research directions; and (4) ensure technologies and method developed through the UNM METALS SRC are made available through direct training of partners and, when appropriate, through commercialization supported through UNM?s STC.UNM technology transfer support. The unique perspective of the RTC leadership on translating findings to indigenous communities and perspectives of tribes to regulators, clinicians, and scientists will ultimately influence the way research is designed and conducted with the engagement of Native communities, and also fulfills the need for data on exposures and health impacts of AUM on indigenous communities.

Public Health Relevance

RESEARCH TRANSLATION CORE NARRATIVE The Research Translation Core (RTC) will identify and translate the scientific results of UNM METALS across the SRP network of research partners, impacted Native American communities, tribal, state and national governmental agencies with shared information needs on the health effects and risk reduction strategies for metals mixtures exposures from abandoned uranium mines (AUMs). Our methods will accommodate our partners? range of comfort and familiarity with technical communication and access to the scientific literature to enhance environmental health literacy and evidence-based decision making for risk reduction. Through interaction with the Community Engagement Core, the RTC will facilitate consideration of the indigenous point of view on par with that of Western science in research projects and remedial decisions.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
5P42ES025589-04
Application #
9903349
Study Section
Special Emphasis Panel (ZES1)
Project Start
Project End
Budget Start
2020-04-01
Budget End
2021-03-31
Support Year
4
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of New Mexico Health Sciences Center
Department
Type
DUNS #
829868723
City
Albuquerque
State
NM
Country
United States
Zip Code
87131
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Hoover, Joseph H; Coker, Eric; Barney, Yolanda et al. (2018) Spatial clustering of metal and metalloid mixtures in unregulated water sources on the Navajo Nation - Arizona, New Mexico, and Utah, USA. Sci Total Environ 633:1667-1678
Zychowski, Katherine E; Kodali, Vamsi; Harmon, Molly et al. (2018) Respirable Uranyl-Vanadate-Containing Particulate Matter Derived From a Legacy Uranium Mine Site Exhibits Potentiated Cardiopulmonary Toxicity. Toxicol Sci 164:101-114
Bolt, Alicia M; Medina, Sebastian; Lauer, Fredine T et al. (2018) Minimal uranium accumulation in lymphoid tissues following an oral 60-day uranyl acetate exposure in male and female C57BL/6J mice. PLoS One 13:e0205211
Harmon, Molly E; Lewis, Johnnye; Miller, Curtis et al. (2018) Arsenic association with circulating oxidized low-density lipoprotein in a Native American community. J Toxicol Environ Health A 81:535-548
Avasarala, Sumant; Lichtner, Peter C; Ali, Abdul-Mehdi S et al. (2017) Reactive Transport of U and V from Abandoned Uranium Mine Wastes. Environ Sci Technol 51:12385-12393