The Scientific Core will be a shared, research resource that provides investigators with services, expertise and equipment that will support, enhance and integrate the'^animal and human studies, thereby promoting the common goals of the Center. The Scientific Core will consolidate and standardize prenatal alcohol exposure procedures and mouse colony management. In addition to reducing research costs, this will allow investigators to query relationships between their findings and those obtained in other research components and, thus, facilitate integration of the research components. The Scientific Core will also manage the mouse behavioral facility that will be used for studies proposed in several Center components. The Scientific Core will also support the development of new research directions by assisting investigators with implementation of novel, behavioral and alcohol exposure paradigms. The Scientific Core v/ill provide statistical support for all of the research components, and will promote interaction among all Center investigators by providing a formal monthly forum for data presentation and discussion of potential collaborations. These monthly Synergy Meetings will aim to integrate the PSO components and foster the development of translational research efforts. Finally, in addition to providing services to the individual research components of the Center, the Scientific Core will, on a limited basis, support independently funded research project grants related to the Center's theme, thereby helping to expand the breadth of the Center's research activities.

Public Health Relevance

The Scientific Core will be a shared, research resource that provides investigators with services, expertise and equipment that will support, enhance and integrate the animal and human studies, thereby promoting the common goals of the Center.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Specialized Center (P50)
Project #
5P50AA022534-05
Application #
9497743
Study Section
Special Emphasis Panel (ZAA1)
Project Start
Project End
Budget Start
2018-07-01
Budget End
2019-06-30
Support Year
5
Fiscal Year
2018
Total Cost
Indirect Cost
Name
University of New Mexico Health Sciences Center
Department
Type
DUNS #
829868723
City
Albuquerque
State
NM
Country
United States
Zip Code
87131
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Gustus, Kymberly C; Li, Lu; Chander, Praveen et al. (2018) Genetic inactivation of synaptosomal-associated protein 25 (SNAP-25) in adult hippocampal neural progenitors impairs pattern discrimination learning but not survival or structural maturation of newborn dentate granule cells. Hippocampus 28:735-744
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Vanderwall, Arden G; Noor, Shahani; Sun, Melody S et al. (2018) Effects of spinal non-viral interleukin-10 gene therapy formulated with d-mannose in neuropathic interleukin-10 deficient mice: Behavioral characterization, mRNA and protein analysis in pain relevant tissues. Brain Behav Immun 69:91-112

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