Core A: The program will be coordinated at Banaras Hindu University, through the efforts of the Administrative Core and the Data Management and Biostatistics Core.
Specific aims of the program are: 1. To provide administrative coordination of the two scientific cores, the four research projects and the Data Management &Biostatistics core ofthe TMRC program. This will include communication with collaborating investigators at institutions within and outside of India, communication with NIH personnel, and assurance of compliance with NIH requirements. 2. To provide financial accounting and oversight of finances at BHU, KAMRC in Muzaffarpur, Institute of Tropical Medicine in Belgium, the University of Western Australia and the University of lowa. This will include distribution of funds, payment of salaries and overall accounting of expenses. 3. To perform the day to day management of the projects. This will involve purchase and distribution of equipment and research supplies, management of personnel, coordination of publications, and arranging communication between investigators on specific projects. 4. To coordinate meetings and training activities. Key activities are (A) the annual TMRC meeting in Varanasi, India, which is attended by participating TMRC scientists and administrators from BHU and Muzaffarpur, and by collaborating investigators from other universities in India, the USA, Australia and Belgium;(B) travel and housing for Indian investigators to participate in scientific meetings, short courses, or short term training experiences in labs at collaborating universities.

Public Health Relevance

Administrative core will coordinate the hwo scientific cores, data management and Bio-statistics core and four research projects ofthe TMRC Program and plays a very important role for smooth running ofthe projects and cores and ensures compliance with the NIH policies and guidelines.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Specialized Center (P50)
Project #
5P50AI074321-08
Application #
8711202
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2014-08-01
Budget End
2015-07-31
Support Year
8
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Banaras Hindu University
Department
Type
DUNS #
City
Varanasi
State
Country
India
Zip Code
221005
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Sundar, Shyam; Agarwal, Dipti (2018) Visceral Leishmaniasis-Optimum Treatment Options in Children. Pediatr Infect Dis J 37:492-494
Singh, Neetu; Sundar, Shyam (2018) Combined neutralization of interferon gamma and tumor necrosis factor alpha induces IL-4 production but has no direct additive impact on parasite burden in splenic cultures of human visceral leishmaniasis. PLoS One 13:e0199817
Singh, Neetu; Kumar, Rajiv; Chauhan, Shashi Bhushan et al. (2018) Peripheral Blood Monocytes With an Antiinflammatory Phenotype Display Limited Phagocytosis and Oxidative Burst in Patients With Visceral Leishmaniasis. J Infect Dis 218:1130-1141
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Sundar, Shyam; Singh, Bhawana (2018) Emerging therapeutic targets for treatment of leishmaniasis. Expert Opin Ther Targets 22:467-486
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Sharma, Smriti; Srivastva, Shweta; Davis, Richard E et al. (2017) The Phenotype of Circulating Neutrophils during Visceral Leishmaniasis. Am J Trop Med Hyg 97:767-770
Kansal, S; Chakravarty, J; Kumar, A et al. (2017) Risk Factors associated with defaulting from visceral leishmaniasis treatment: analysis under routine programme conditions in Bihar, India. Trop Med Int Health 22:1037-1042

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