The standardization of culture conditions and the establishment of cell lines has made cell culture a valuable tool. The cell and tissue culture core will provide physical and personnel support for the projects within the SCOR. Services provided by the cell and tissue culture facility include the monitoring and maintenance of equipment, stocking tissue culture glassware, plasticware, sterile media, and growth serum, and most importantly preparing, maintaining and supplying cultures of bovine chondrocytes and chondrosarcoma chondrocytes. Cells will be prepared in the core facility for each major experiment, which will allow for the most efficient use of space and time. Isotope incorporation studies, experiments involving the use of drug treatment or other reagents can be carried out in the facility with the investigators performing the special biochemical analyses in their own laboratories. The cell and tissue culture core facilitate the progress of the individual projects.

Project Start
Project End
Budget Start
Budget End
Support Year
4
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Rush University Medical Center
Department
Type
DUNS #
City
Chicago
State
IL
Country
United States
Zip Code
60612
Knudson, Warren; Ishizuka, Shinya; Terabe, Kenya et al. (2018) The pericellular hyaluronan of articular chondrocytes. Matrix Biol :
Tezcan, Mehmet E; Goker, Berna; Lidtke, Roy et al. (2017) Long-term effects of lateral wedge orthotics on hip and ankle joint space widths. Gait Posture 51:36-40
Patchigolla, R Krishna R; Knudson, Warren; Schmid, Thomas M (2012) Matrix metalloproteinase-9 in a unique proteoglycan form in avian embryonic growth plate cartilage. Arch Biochem Biophys 520:42-50
Anderson, Donald D; Chubinskaya, Susan; Guilak, Farshid et al. (2011) Post-traumatic osteoarthritis: improved understanding and opportunities for early intervention. J Orthop Res 29:802-9
Schmitz, I; Ariyoshi, W; Takahashi, N et al. (2010) Hyaluronan oligosaccharide treatment of chondrocytes stimulates expression of both HAS-2 and MMP-3, but by different signaling pathways. Osteoarthritis Cartilage 18:447-54
Bajaj, Sarvottam; Shoemaker, Thomas; Hakimiyan, Arnavaz A et al. (2010) Protective effect of P188 in the model of acute trauma to human ankle cartilage: the mechanism of action. J Orthop Trauma 24:571-6
Morris, Kirsten J; Cs-Szabo, Gabriella; Cole, Ada A (2010) Characterization of TIMP-3 in human articular talar cartilage. Connect Tissue Res 51:478-90
Rolauffs, Bernd; Muehleman, Carol; Li, Jun et al. (2010) Vulnerability of the superficial zone of immature articular cartilage to compressive injury. Arthritis Rheum 62:3016-27
Farlow, E C; Vercillo, M S; Coon, J S et al. (2010) A multi-analyte serum test for the detection of non-small cell lung cancer. Br J Cancer 103:1221-8
Shakoor, Najia; Sengupta, Mondira; Foucher, Kharma C et al. (2010) Effects of common footwear on joint loading in osteoarthritis of the knee. Arthritis Care Res (Hoboken) 62:917-23

Showing the most recent 10 out of 305 publications