Periodontal Diseases Research Center

Taichman, Norton S.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Dental & Craniofacial Research (NIDCR)
• Type: Specialized Center (P50)
• Project #: 1P50DE007118-01
• Application #: 3105653
• Study Section: (SRC)
• Project Start: 1985-09-01
• Project End: 1988-08-31
• Budget Start: 1985-09-01
• Budget End: 1986-08-31
• Support Year: 1
• Fiscal Year: 1985

Institution

• Name: University of Pennsylvania
• Type: Schools of Dentistry/Oral Hygn
• DUNS #: 042250712
• City: Philadelphia
• State: PA
• Country: United States
• Zip Code: 19104

Publications

Brogan, J M; Lally, E T; Poulsen, K et al. (1994) Regulation of Actinobacillus actinomycetemcomitans leukotoxin expression: analysis of the promoter regions of leukotoxic and minimally leukotoxic strains. Infect Immun 62:501-8

DiRienzo, J M; McKay, T L (1994) Identification and characterization of genetic cluster groups of Actinobacillus actinomycetemcomitans isolated from the human oral cavity. J Clin Microbiol 32:75-81

DiRienzo, J M; Slots, J; Sixou, M et al. (1994) Specific genetic variants of Actinobacillus actinomycetemcomitans correlate with disease and health in a regional population of families with localized juvenile periodontitis. Infect Immun 62:3058-65

Lally, E T; Golub, E E; Kieba, I R (1994) Identification and immunological characterization of the domain of Actinobacillus actinomycetemcomitans leukotoxin that determines its specificity for human target cells. J Biol Chem 269:31289-95

Shenker, B J; Vitale, L A; Keiba, I et al. (1994) Flow cytometric analysis of the cytotoxic effects of Actinobacillus actinomycetemcomitans leukotoxin on human natural killer cells. J Leukoc Biol 55:153-60

Shenker, B J; Wannberg, S; Vitale, L et al. (1993) Reconstruction of severe combined immunodeficient mice with lymphocytes from patients with localized juvenile periodontitis. J Periodontal Res 28:487-90

Berthold, P; Forti, D; Kieba, I R et al. (1992) Electron immunocytochemical localization of Actinobacillus actinomycetemcomitans leukotoxin. Oral Microbiol Immunol 7:24-7

Lally, E T; Golub, E E; Kieba, I R et al. (1991) Structure and function of the B and D genes of the Actinobacillus actinomycetemcomitans leukotoxin complex. Microb Pathog 11:111-21

Taichman, N S; Iwase, M; Korchak, H et al. (1991) Membranolytic activity of Actinobacillus actinomycetemcomitans leukotoxin. J Periodontal Res 26:258-60

Shenker, B J; Vitale, L; Slots, J (1991) Immunosuppressive effects of Prevotella intermedia on in vitro human lymphocyte activation. Infect Immun 59:4583-9