PROJECT MANAGEMENT PLAN. The Center will continue to be managed through an Executive Committee under advisement from NIGMS program officers and Center advisory boards in a transparent and effective manner. Directors. Dr. John Aitchison, the Principal Investigator, is a founding member of ISB, and is a Professor and (Executive) Director of Integrative Biology. He will act as the Center Director and has ultimate responsibility for the program. Dr. Aitchison also holds an appointment at Seattle Biomedical Research Institute. This dual appointment was established by ISB and Seattle BioMed through a joint institutional initiative to facilitate exchange between the institutes and the dissemination of the practice of systems biology and systems approaches to research in infectious diseases. Dr. Aitchison is committed to his role as Center Director to drive advances in systems biology and as Director for Integrative Biology to ensure broader impact of the Center programs - a fundamental goal of the Center. Dr. Leroy Hood, Associate Director will interact closely with the Director on all decisions, and act as Director in his absence.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center (P50)
Project #
2P50GM076547-06A1
Application #
8517245
Study Section
Special Emphasis Panel (ZGM1-CBCB-3 (SB))
Project Start
2012-07-01
Project End
2017-08-31
Budget Start
2012-09-01
Budget End
2013-08-31
Support Year
6
Fiscal Year
2012
Total Cost
$319,756
Indirect Cost
$142,114
Name
Institute for Systems Biology
Department
Type
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98109
Maixner, Frank; Turaev, Dmitrij; Cazenave-Gassiot, Amaury et al. (2018) The Iceman's Last Meal Consisted of Fat, Wild Meat, and Cereals. Curr Biol 28:2348-2355.e9
Holden, Jennifer M; Koreny, Ludek; Obado, Samson et al. (2018) Involvement in surface antigen expression by a moonlighting FG-repeat nucleoporin in trypanosomes. Mol Biol Cell 29:1100-1110
Hoopmann, Michael R; Winget, Jason M; Mendoza, Luis et al. (2018) StPeter: Seamless Label-Free Quantification with the Trans-Proteomic Pipeline. J Proteome Res 17:1314-1320
Slama, Patrick; Hoopmann, Michael R; Moritz, Robert L et al. (2018) Robust determination of differential abundance in shotgun proteomics using nonparametric statistics. Mol Omics 14:424-436
Jabbari, Neda; Glusman, Gustavo; Joesch-Cohen, Lena M et al. (2018) Whole genome sequence and comparative analysis of Borrelia burgdorferi MM1. PLoS One 13:e0198135
Trachana, Kalliopi; Bargaje, Rhishikesh; Glusman, Gustavo et al. (2018) Taking Systems Medicine to Heart. Circ Res 122:1276-1289
Shao, Wenguang; Pedrioli, Patrick G A; Wolski, Witold et al. (2018) The SysteMHC Atlas project. Nucleic Acids Res 46:D1237-D1247
Kazantsev, Fedor; Akberdin, Ilya; Lashin, Sergey et al. (2018) MAMMOTh: A new database for curated mathematical models of biomolecular systems. J Bioinform Comput Biol 16:1740010
Mast, Fred D; Herricks, Thurston; Strehler, Kathleen M et al. (2018) ESCRT-III is required for scissioning new peroxisomes from the endoplasmic reticulum. J Cell Biol 217:2087-2102
Pacheco, Derek; Warfield, Linda; Brajcich, Michelle et al. (2018) Transcription Activation Domains of the Yeast Factors Met4 and Ino2: Tandem Activation Domains with Properties Similar to the Yeast Gcn4 Activator. Mol Cell Biol 38:

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