Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center (P50)
Project #
5P50GM103368-03
Application #
8731943
Study Section
Special Emphasis Panel (ZRG1-AARR-K)
Project Start
Project End
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
3
Fiscal Year
2014
Total Cost
$194,980
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
781613492
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Haldane, Allan; Flynn, William F; He, Peng et al. (2018) Coevolutionary Landscape of Kinase Family Proteins: Sequence Probabilities and Functional Motifs. Biophys J 114:21-31
Ilina, Tatiana V; Slack, Ryan L; Elder, John H et al. (2018) Effect of tRNA on the Maturation of HIV-1 Reverse Transcriptase. J Mol Biol 430:1891-1900
Gao, Bing; Li, Suhua; Wu, Peng et al. (2018) SuFEx Chemistry of Thionyl Tetrafluoride (SOF4 ) with Organolithium Nucleophiles: Synthesis of Sulfonimidoyl Fluorides, Sulfoximines, Sulfonimidamides, and Sulfonimidates. Angew Chem Int Ed Engl 57:1939-1943
Gahtory, Digvijay; Sen, Rickdeb; Pujari, Sidharam et al. (2018) Quantitative and Orthogonal Formation and Reactivity of SuFEx Platforms. Chemistry 24:10550-10556
Wu, Weixin; Hatterschide, Joshua; Syu, Yu-Ci et al. (2018) Human T-cell leukemia virus type 1 Gag domains have distinct RNA-binding specificities with implications for RNA packaging and dimerization. J Biol Chem 293:16261-16276
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Li, Suhua; Wu, Peng; Moses, John E et al. (2017) Multidimensional SuFEx Click Chemistry: Sequential Sulfur(VI) Fluoride Exchange Connections of Diverse Modules Launched From An SOF4 Hub. Angew Chem Int Ed Engl 56:2903-2908
Ozorowski, Gabriel; Pallesen, Jesper; de Val, Natalia et al. (2017) Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike. Nature 547:360-363
Levy, Ronald M; Haldane, Allan; Flynn, William F (2017) Potts Hamiltonian models of protein co-variation, free energy landscapes, and evolutionary fitness. Curr Opin Struct Biol 43:55-62

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