CORE 5: AFTERCARE RESEARCH PROGRAM The Aftercare Research Program is an outpatient research clinic at the UCLA Semel Institute for Neuroscience &Human Behavior that will provide the clinical site for the recruitment, pharmacological and psychosocial interventions, and assessments of symptoms and functional outcome for first-episode patients who are participating in research projects in this Center. The primary mission of the Aftercare Program is to provide a structured and high quality clinical care setting within which this Center research can take place. The Aftercare Research Program will provide a centralized and standardized process for screening and diagnosing first-episode schizophrenia patient participants, providing their clinical services, and completing high-quality longitudinal assessments of symptoms, work functioning, and social functioning. As detailed in the budget justification section for this Core, this centralization will result in great savings to the multiple individual projects that involve Aftercare Program patients, compared to costs if these research projects were carried out independently. Furthermore, by utilizing a shared group of first-episode patients, opportunities for integrative data analyses across projects will become available. A second function is to optimize the level of patient participation in Center-related research projects. A third function is to provide a sample of normal subjects, demogi'aphically comparable to the first-episode patients, for potential participation in Center-affiliated projects. A fourth function ofthe Aftercare Research Program is to provide a convenient group of patient volunteers for the piloting of new measures being developed by individual projects and by the Functional Outcome and Symptom Assessment Core. A fifth function is to offer a research training site for predoctoral and post-doctoral research fellows to encourage development of new translational researchers. Three psychiatrists, and one doctoral level and two masters level therapists, will provide the clinical interventions and research assessments in space allocated to the Program in the UCLA Medical Plaza.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Specialized Center (P50)
Project #
5P50MH066286-09
Application #
8497731
Study Section
Special Emphasis Panel (ZMH1-ERB-N)
Project Start
Project End
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
9
Fiscal Year
2013
Total Cost
$305,509
Indirect Cost
$106,527
Name
University of California Los Angeles
Department
Type
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Lee, Junghee; Nuechterlein, Keith H; Knowlton, Barbara J et al. (2018) Episodic Memory for Dynamic Social Interaction Across Phase of Illness in Schizophrenia. Schizophr Bull 44:620-630
Velthorst, Eva; Meyer, Eric C; Giuliano, Anthony J et al. (2018) Neurocognitive profiles in the prodrome to psychosis in NAPLS-1. Schizophr Res :
Chen, Qiaolin; Sugar, Catherine A; Weiss, Robert E (2018) A Bayesian confirmatory factor model for multivariate observations in the form of two-way tables of data. Stat Med 37:1696-1710
Hamilton, Holly K; Williams, Terrance J; Ventura, Joseph et al. (2018) Clinical and Cognitive Significance of Auditory Sensory Processing Deficits in Schizophrenia. Am J Psychiatry 175:275-283
Clayson, Peter E; Kern, Robert S; Nuechterlein, Keith H et al. (2018) Social vs. non-social measures of learning potential for predicting community functioning across phase of illness in schizophrenia. Schizophr Res :
Hampton, Joya N; Trotman, Hanan D; Addington, Jean et al. (2018) The relation of atypical antipsychotic use and stress with weight in individuals at clinical high risk for psychosis. Stress Health 34:591-600
Kline, Emily R; Seidman, Larry J; Cornblatt, Barbara A et al. (2018) Depression and clinical high-risk states: Baseline presentation of depressed vs. non-depressed participants in the NAPLS-2 cohort. Schizophr Res 192:357-363
Fernandez, Vindia G; Asarnow, Robert; Narr, Katherine L et al. (2018) Temporal lobe thickness and verbal memory in first-degree relatives of individuals with schizophrenia. Schizophr Res 199:221-225
Woodberry, Kristen A; Seidman, Larry J; Bryant, Caitlin et al. (2018) Treatment Precedes Positive Symptoms in North American Adolescent and Young Adult Clinical High Risk Cohort. J Clin Child Adolesc Psychol 47:69-78
Grazioplene, Rachael G; Bearden, Carrie E; Subotnik, Kenneth L et al. (2018) Connectivity-enhanced diffusion analysis reveals white matter density disruptions in first episode and chronic schizophrenia. Neuroimage Clin 18:608-616

Showing the most recent 10 out of 146 publications