Intimate partner violence (IPV) is associated with posttraumatic stress disorder (PTSD) and depression for? women. Despite significant advances in understanding PTSD and depression and associated? neurobiological features, the long term impact of IPV on these conditions remains elusive. We propose to? conduct longitudinal research on the impact of IPV on PTSD and depression in a cohort of 205 Latina? mothers. This longitudinal study entitled """"""""Intimate Partner Violence and Mental Health of Latinas""""""""? responds to the Institute of Medicine's call for long-term follow up studies to examine the causes and? consequences of violence against women. An innovative framework focusing on Vulnerability and Protective? factors is proposed. Mental health outcomes include PTSD and depression symptoms and associated? neurobiological profiles reflecting cumulative stress exposure (allostatic load).
Major aims are to: 1) assess? the longitudinal course (prevalence, severity and neurobiological characteristics) of PTSD and depression? symptoms for Latina mothers who differ in IPV exposure and the emotional and behavioral problems of the? children through their first five years of life; 2) assess the additive or interactive effects of recent IPV and? non-IPV trauma on PTSD and depression symptoms, and associated biomarkers of allostatic load in this? cohort. In addition, the role of vulnerability factors (low SES, acculturation, substance abuse) in modifying the? relationships between non-IPV trauma on PTSD, depression, and neurobiological indicators overtime will be? examined; and 3) assess the additive or interactive effects of maternal attachment on PTSD and depression? symptoms and biomarkers of allostatic load in the cohort. We will also assess whether protective factors? (e.g. mastery, coping, resiliency, social support, and utilization of health care) will modify the relationships? between IPV and each of the outcomes over time. The sample will be followed for four years and will? participate in a total of seven interviews conducted every 6 months. Analytic strategies to be used, include? multiple regression, structural equation modeling, and longitudinal growth curve analysis. Results from.this? unique project will provide important information for understanding the impact of IPV on PTSD and? depression symptoms and factors that modify this relationship over time.? Intimate partner violence (IPV) is frequently seen in conjunction with other health problems but little is known? on the long term impact of IPV on Latino women. This research will follow a group of Latino women over? time and allow us to learn about factors which may lessen or alleviate the mental health related long term? impact of IPV.?

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Specialized Center (P50)
Project #
5P50MH073453-02
Application #
7488462
Study Section
Special Emphasis Panel (ZMH1)
Project Start
2007-08-21
Project End
2011-07-31
Budget Start
2007-08-21
Budget End
2008-07-31
Support Year
2
Fiscal Year
2007
Total Cost
$320,139
Indirect Cost
Name
University of California Los Angeles
Department
Type
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
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Wyatt, Gail E; Loeb, Tamra B; Williams, John K et al. (2012) A Case Study of Sexual Abuse and Psychological Correlates among an HIV-Serodiscordant Couple. Couple Family Psychol 1:146-159

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