The research program of the California Primate Research Center will be focused in areas selected for relevance to human health. The research is broad in scope but emphasizes problems for which the nonhuman primate is the appropriate animal model. Investigations are carried out at the behavioral, physiological, biochemical and molecular levels. Studies of normal and abnormal functions are performed and spontaneous diseases as well as experimentally-induced disorders are investigated. There is a longstanding research interest in the adverse effects of environmental factors. Social dynamics are studied under field and laboratory conditions. The major program units will be Behavioral Biology (social organization, interspecies, differences, psychosocial development, maternal/infant behavior and development); Developmental and Reproductive Biology (gamete biology and fertilization, early embryonic differentiation and implantation, reproductive immunology, endocrinology and toxicology, contraceptive development); Respiratory Diseases (environmental oxidants and other air pollutants, cellular biology and molecular biology of the lung); Comparative Retrovirology (clinical and basic research in human and simian AIDS); Virology and Immunology (simian AIDS, pathogenesis, mechanisms of immunopathogenesis, lentiviruses, genetic determinants of immunosuppressive disease); and Comparative Primate Biology (hepatic physiopathology, comparative genetics, environmental physiology, intravital and quantitative microscopy and a variety of biomedical collaborative research projects). Primate Services (the major support unit, is composed of teams of specialists responsible for the high quality of animal care and ensures the humane treatment of animals. This unit also conducts studies to determine the most optimal approaches for handling and housing of animals in a research setting). There is considerable interaction between the research units, particularly the units for Comparative Retrovirology and Virology and Immunology.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Primate Research Center Grants (P51)
Project #
5P51RR000169-38
Application #
2910778
Study Section
Special Emphasis Panel (CM)
Program Officer
Robinson, Jerry
Project Start
1975-06-01
Project End
2000-04-30
Budget Start
1999-05-01
Budget End
2000-04-30
Support Year
38
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of California Davis
Department
Type
Schools of Veterinary Medicine
DUNS #
094878337
City
Davis
State
CA
Country
United States
Zip Code
95618
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Pittet, Florent; Johnson, Crystal; Hinde, Katie (2017) Age at reproductive debut: Developmental predictors and consequences for lactation, infant mass, and subsequent reproduction in rhesus macaques (Macaca mulatta). Am J Phys Anthropol 164:457-476
Kyle, Colin T; Stokes, Jared; Bennett, Jeffrey et al. (2017) Cytoarchitectonically-driven MRI atlas of nonhuman primate hippocampus: Preservation of subfield volumes in aging. Hippocampus :

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