Abstract

A major issue in clinical trials is recruitment of subjects. Considerable time and skill must be devoted to recruitment of older subjects, minorities and disabled people with chronic diseases. The recruitment core will have overall responsibility for promoting community relations, recruiting participants for developmental studies, pilot studies and main clinical trials and conducting research on questions related to recruitment effectiveness. This core builds on substantial experience and projects previously and currently underway at the Bowman Gray School of Medicine and at the University of Tennessee Memphis. Both institutions have sophisticated clinical trial recruitment experience, and it will be possible to combine them in a single collaborative core which will share resources and ideas and develop new knowledge methods regarding recruitment of older subjects in clinical trials. The activities of the recruitment core will have three foci: community relations, the development of recruitment strategies and recruitment data bases in the conduct of research on the ways to improve recruitment and retention of older subjects.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Comprehensive Center (P60)
Project #
5P60AG010484-02
Application #
3790585
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
2
Fiscal Year
1992
Total Cost
Indirect Cost

  Institution

Name
Wake Forest University Health Sciences
Department
Type
DUNS #
041418799
City
Winston-Salem
State
NC
Country
United States
Zip Code
27106

  Publications

Li, Yanhong; Levy, Wayne C; Neilson, Matthew P et al. (2014) Associations between seattle heart failure model scores and medical resource use and costs: findings from HF-ACTION. J Card Fail 20:541-7
Li, Yanhong; Neilson, Matthew P; Whellan, David J et al. (2013) Associations between Seattle Heart Failure Model scores and health utilities: findings from HF-ACTION. J Card Fail 19:311-6
Flynn, Kathryn E; Lin, Li; Moe, Gordon W et al. (2012) Relationships between changes in patient-reported health status and functional capacity in outpatients with heart failure. Am Heart J 163:88-94.e3
Swank, Ann M; Horton, John; Fleg, Jerome L et al. (2012) Modest increase in peak VO2 is related to better clinical outcomes in chronic heart failure patients: results from heart failure and a controlled trial to investigate outcomes of exercise training. Circ Heart Fail 5:579-85
Miller, G D; Nicklas, B J; Davis, C C et al. (2012) Basal growth hormone concentration increased following a weight loss focused dietary intervention in older overweight and obese women. J Nutr Health Aging 16:169-74
Reed, Shelby D; Li, Yanhong; Dunlap, Mark E et al. (2012) In-hospital resource use and medical costs in the last year of life by mode of death (from the HF-ACTION randomized controlled trial). Am J Cardiol 110:1150-5
Reed, Shelby D; Li, Yanhong; Ellis, Stephen J et al. (2012) Associations between hemoglobin level, resource use, and medical costs in patients with heart failure: findings from HF-ACTION. J Card Fail 18:784-91
Morris, Peter E; Griffin, Leah; Berry, Michael et al. (2011) Receiving early mobility during an intensive care unit admission is a predictor of improved outcomes in acute respiratory failure. Am J Med Sci 341:373-7
Messier, S P; Legault, C; Loeser, R F et al. (2011) Does high weight loss in older adults with knee osteoarthritis affect bone-on-bone joint loads and muscle forces during walking? Osteoarthritis Cartilage 19:272-80
Arena, Ross; Myers, Jonathan; Abella, Joshua et al. (2011) Cardiopulmonary exercise testing is equally prognostic in young, middle-aged and older individuals diagnosed with heart failure. Int J Cardiol 151:278-83

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