The Diabetes Research and Training Center (DRTC) at Vanderbilt is one of a network of Core Centers established by the National Institute of Diabetes, Digestive and Kidney Diseases (NIDDK) to conduct research and training in diabetes mellitus and related endocrine and metabolic disorders consistent with the National Diabetes Mellitus Research and Education Act, the report of the National Commission on Diabetes, and the Administrative Guidelines for DRTCs, as promulgated by the NIDDK. The Vanderbilt DRTC is a multi-disciplinary program with 81 participating faculty members distributed among 14 departments in 2 schools and 3 colleges of the University. The Biomedical Research Component consists of a research base of 64 investigators in the following interest areas: In vivo metabolism, Signal transduction, Etiology and complications, Gene regulation, Beta cell function, Demonstration and education. These investigators are supported by a Surgical and Analytical Services Core that is comprised of Hormone Assay, Amino Acid Assay and Animal Services subcores, and by the Cell and Molecular Biology Services Core that consists of DNA Chemistry, Media/Reagents, Cell Imaging and Transgenic Mouse/ES Cell subcores. A Pilot and Feasibility Studies Program helps new investigators initiate their research programs. The Demonstration/Education Component includes a Model Demonstration Unit that serves as the training laboratory for students in the health professions and it maintains a cohort of patients with diabetes who serve as volunteers for approved clinical research programs. The MDU also provides professional, technical and administrative support for Center investigators who conduct research in the General Clinical Research Center. This component also includes the Education/Evaluation Core that initiates and supports education research and instructional development activities. The Center coordinates three NIH-sponsored training programs that provide education and laboratory training in diabetes/endocrinology to medical students and graduate students and postdoctoral training for MDs and PhDs. An enrichment program provides continuing education through a Diabetes Research Day, a seminar series and annual symposia. The Administrative Component provides both scientific and administrative leadership for the total program.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Comprehensive Center (P60)
Project #
5P60DK020593-21
Application #
2838042
Study Section
Special Emphasis Panel (SRC (01))
Program Officer
Abraham, Kristin M
Project Start
1996-02-13
Project End
2001-11-30
Budget Start
1999-03-15
Budget End
1999-11-30
Support Year
21
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Physiology
Type
Schools of Medicine
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212
Cooke, Allison L; Morris, Jamie; Melchior, John T et al. (2018) A thumbwheel mechanism for APOA1 activation of LCAT activity in HDL. J Lipid Res 59:1244-1255
Moore, Mary Courtney; Kelley, David E; Camacho, Raul C et al. (2018) Superior Glycemic Control With a Glucose-Responsive Insulin Analog: Hepatic and Nonhepatic Impacts. Diabetes 67:1173-1181
Funkhouser-Jones, Lisa J; van Opstal, Edward J; Sharma, Ananya et al. (2018) The Maternal Effect Gene Wds Controls Wolbachia Titer in Nasonia. Curr Biol 28:1692-1702.e6
Hart, Nathaniel J; Aramandla, Radhika; Poffenberger, Gregory et al. (2018) Cystic fibrosis-related diabetes is caused by islet loss and inflammation. JCI Insight 3:
Warren Andersen, Shaneda; Blot, William J; Shu, Xiao-Ou et al. (2018) Associations Between Neighborhood Environment, Health Behaviors, and Mortality. Am J Prev Med 54:87-95
Sui, Lina; Danzl, Nichole; Campbell, Sean R et al. (2018) ?-Cell Replacement in Mice Using Human Type 1 Diabetes Nuclear Transfer Embryonic Stem Cells. Diabetes 67:26-35
Dutter, Brendan F; Ender, Anna; Sulikowski, Gary A et al. (2018) Rhodol-based thallium sensors for cellular imaging of potassium channel activity. Org Biomol Chem 16:5575-5579
Herrick, Mary K; Favela, Kristin M; Simerly, Richard B et al. (2018) Attenuation of diet-induced hypothalamic inflammation following bariatric surgery in female mice. Mol Med 24:56
Perez, Katia M; Curley, Kathleen L; Slaughter, James C et al. (2018) Glucose Homeostasis and Energy Balance in Children With Pseudohypoparathyroidism. J Clin Endocrinol Metab 103:4265-4274
Marre, Meghan L; McGinty, John W; Chow, I-Ting et al. (2018) Modifying Enzymes Are Elicited by ER Stress, Generating Epitopes That Are Selectively Recognized by CD4+ T Cells in Patients With Type 1 Diabetes. Diabetes 67:1356-1368

Showing the most recent 10 out of 1487 publications