This proposal seeks the continuation of the University of Chicago Diabetes Research and Training Center (DRTC). The Center is an interdepartmental and interinstitutional cooperative endeavor involving investigators from the University of Chicago, Illinois Institute of Technology, Loyola University Chicago School of Nursing, Northern Illinois University, Northwestern University Feinberg School of Medicine and the University of Illinois at Chicago Schools of Medicine and Nursing with differing scientific backgrounds, yet sharing a common interest in diabetes and related research.
The aims of the Center are: 1. To foster collaborative, multidisciplinary diabetes and endocrinology research in a supportive environment;2. To enhance the clinical and basic research capabilities of established diabetes investigators;3. To encourage investigators not involved in diabetes research to pursue problems related to diabetes and endocrinology;4. To speed the transfer of advances in basic biomedical and genetic research to the clinical arena whey they may be applied to the diagnosis and treatment of persons with diabetes;and 5. To inform others in both professional and lay settings of the accomplishments, opportunities and advances in diabetes research and training. This application consists of three sections: Section 1 - Overview;Section 2 - Administrative component;and Section 3 - Biomedical Research Component (Research base, Biomedical research cores (Islet Cell Biology, Molecular Biology and Genetics, Ligand Assay, Physiology, and Animal Models), Prevention and Control core, Pilot and Feasibility Program, and Enrichment Program). It also contains an Appendix.

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Comprehensive Center (P60)
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Study Section
Special Emphasis Panel (ZDK1-GRB-S (O1))
Program Officer
Hyde, James F
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University of Chicago
Internal Medicine/Medicine
Schools of Medicine
United States
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Temple, Karla A; Leproult, Rachel; Morselli, Lisa et al. (2018) Sex Differences in the Impact of Obstructive Sleep Apnea on Glucose Metabolism. Front Endocrinol (Lausanne) 9:376
Kirkley, Andrew G; Carmean, Christopher M; Ruiz, Daniel et al. (2018) Arsenic exposure induces glucose intolerance and alters global energy metabolism. Am J Physiol Regul Integr Comp Physiol 314:R294-R303
Morselli, Lisa L; Temple, Karla A; Leproult, Rachel et al. (2018) Determinants of Slow-Wave Activity in Overweight and Obese Adults: Roles of Sex, Obstructive Sleep Apnea and Testosterone Levels. Front Endocrinol (Lausanne) 9:377
Fowler, Jonas L; Lee, Steve Seung-Young; Wesner, Zachary C et al. (2018) Three-Dimensional Analysis of the Human Pancreas. Endocrinology 159:1393-1400
Boland, Brandon B; Brown Jr, Charles; Alarcon, Cristina et al. (2018) ?-Cell Control of Insulin Production During Starvation-Refeeding in Male Rats. Endocrinology 159:895-906
Graff, Mariaelisa; Emery, Leslie S; Justice, Anne E et al. (2017) Genetic architecture of lipid traits in the Hispanic community health study/study of Latinos. Lipids Health Dis 16:200
Penckofer, Sue; Byrn, Mary; Adams, William et al. (2017) Vitamin D Supplementation Improves Mood in Women with Type 2 Diabetes. J Diabetes Res 2017:8232863
Martyn-Nemeth, Pamela; Quinn, Laurie; Menon, Usha et al. (2017) Dietary Profiles of First-Generation South Asian Indian Adolescents in the United States. J Immigr Minor Health 19:309-317
Hon, Jason; Hwang, Michelle S; Charnetzki, Meara A et al. (2017) Kinetic characterization of the inhibition of protein tyrosine phosphatase-1B by Vanadyl (VO2+) chelates. J Biol Inorg Chem 22:1267-1279
Palygin, Oleg; Evans, Louise C; Cowley Jr, Allen W et al. (2017) Acute In Vivo Analysis of ATP Release in Rat Kidneys in Response to Changes of Renal Perfusion Pressure. J Am Heart Assoc 6:

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