Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
1R01AG008174-01
Application #
3119623
Study Section
(SRC)
Project Start
1988-06-01
Project End
1993-05-31
Budget Start
1988-06-01
Budget End
1989-05-31
Support Year
1
Fiscal Year
1988
Total Cost
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Type
Schools of Medicine
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75390
Shim, Gil-Jin; Warner, Margaret; Kim, Hyun-Jin et al. (2004) Aromatase-deficient mice spontaneously develop a lymphoproliferative autoimmune disease resembling Sjogren's syndrome. Proc Natl Acad Sci U S A 101:12628-33
Simpson, E R (2000) Genetic mutations resulting in loss of aromatase activity in humans and mice. J Soc Gynecol Investig 7:S18-21
Simpson, E R (2000) Role of aromatase in sex steroid action. J Mol Endocrinol 25:149-56
Simpson, E; Rubin, G; Clyne, C et al. (2000) The role of local estrogen biosynthesis in males and females. Trends Endocrinol Metab 11:184-8
Simpson, E R (2000) Biology of aromatase in the mammary gland. J Mammary Gland Biol Neoplasia 5:251-8
Simpson, E; Jones, M; Davis, S et al. (1999) Do intracrine mechanisms regulate aromatase expression? J Steroid Biochem Mol Biol 69:447-52
Simpson, E; Rubin, G; Clyne, C et al. (1999) Local estrogen biosynthesis in males and females. Endocr Relat Cancer 6:131-7
Agarwal, V R; Takayama, K; Van Wyk, J J et al. (1998) Molecular basis of severe gynecomastia associated with aromatase expression in a fibrolamellar hepatocellular carcinoma. J Clin Endocrinol Metab 83:1797-800
Simpson, E R (1998) Genetic mutations resulting in estrogen insufficiency in the male. Mol Cell Endocrinol 145:55-9
Bulun, S E; Sharda, G; Rink, J et al. (1996) Distribution of aromatase P450 transcripts and adipose fibroblasts in the human breast. J Clin Endocrinol Metab 81:1273-7

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