Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI020148-05
Application #
2061117
Study Section
Bacteriology and Mycology Subcommittee 1 (BM)
Project Start
1983-08-01
Project End
1988-07-31
Budget Start
1987-08-01
Budget End
1988-07-31
Support Year
5
Fiscal Year
1987
Total Cost
Indirect Cost
Name
U.S. Uniformed Services University of Health Science
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
City
Bethesda
State
MD
Country
United States
Zip Code
20814
Russo, Lisa M; Melton-Celsa, Angela R; O'Brien, Alison D (2016) Shiga Toxin (Stx) Type 1a Reduces the Oral Toxicity of Stx Type 2a. J Infect Dis 213:1271-9
Melton-Celsa, Angela R; O'Brien, Alison D; Feng, Peter C H (2015) Virulence Potential of Activatable Shiga Toxin 2d-Producing Escherichia coli Isolates from Fresh Produce. J Food Prot 78:2085-8
Bunger, Joshua C; Melton-Celsa, Angela R; Maynard, Ernest L et al. (2015) Reduced Toxicity of Shiga Toxin (Stx) Type 2c in Mice Compared to Stx2d Is Associated with Instability of Stx2c Holotoxin. Toxins (Basel) 7:2306-20
Melton-Celsa, Angela R (2014) Shiga Toxin (Stx) Classification, Structure, and Function. Microbiol Spectr 2:EHEC-0024-2013
Gray, Miranda D; Lampel, Keith A; Strockbine, Nancy A et al. (2014) Clinical isolates of Shiga toxin 1a-producing Shigella flexneri with an epidemiological link to recent travel to HispaƱiola. Emerg Infect Dis 20:1669-77
Melton-Celsa, Angela R; O'Brien, Alison D (2014) New Therapeutic Developments against Shiga Toxin-Producing Escherichia coli. Microbiol Spectr 2:
Boisen, Nadia; Hansen, Anne-Marie; Melton-Celsa, Angela R et al. (2014) The presence of the pAA plasmid in the German O104:H4 Shiga toxin type 2a (Stx2a)-producing enteroaggregative Escherichia coli strain promotes the translocation of Stx2a across an epithelial cell monolayer. J Infect Dis 210:1909-19
Melton-Celsa, Angela; Mohawk, Krystle; Teel, Louise et al. (2012) Pathogenesis of Shiga-toxin producing escherichia coli. Curr Top Microbiol Immunol 357:67-103
Steyert, Susan R; Sahl, Jason W; Fraser, Claire M et al. (2012) Comparative genomics and stx phage characterization of LEE-negative Shiga toxin-producing Escherichia coli. Front Cell Infect Microbiol 2:133
Scheutz, Flemming; Teel, Louise D; Beutin, Lothar et al. (2012) Multicenter evaluation of a sequence-based protocol for subtyping Shiga toxins and standardizing Stx nomenclature. J Clin Microbiol 50:2951-63

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