Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI022470-11
Application #
2061832
Study Section
Experimental Virology Study Section (EVR)
Project Start
1985-07-01
Project End
1999-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Virginia
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904

  Publications

Cardone, Giovanni; Brecher, Matthew; Fontana, Juan et al. (2012) Visualization of the two-step fusion process of the retrovirus avian sarcoma/leukosis virus by cryo-electron tomography. J Virol 86:12129-37
Brecher, Matthew; Schornberg, Kathryn L; Delos, Sue E et al. (2012) Cathepsin cleavage potentiates the Ebola virus glycoprotein to undergo a subsequent fusion-relevant conformational change. J Virol 86:364-72
Gregory, Sonia M; Harada, Erisa; Liang, Binyong et al. (2011) Structure and function of the complete internal fusion loop from Ebolavirus glycoprotein 2. Proc Natl Acad Sci U S A 108:11211-6
Avinoam, Ori; Fridman, Karen; Valansi, Clari et al. (2011) Conserved eukaryotic fusogens can fuse viral envelopes to cells. Science 332:589-92
Dube, Derek; Schornberg, Kathryn L; Shoemaker, Charles J et al. (2010) Cell adhesion-dependent membrane trafficking of a binding partner for the ebolavirus glycoprotein is a determinant of viral entry. Proc Natl Acad Sci U S A 107:16637-42
Mire, Chad E; White, Judith M; Whitt, Michael A (2010) A spatio-temporal analysis of matrix protein and nucleocapsid trafficking during vesicular stomatitis virus uncoating. PLoS Pathog 6:e1000994
Delos, Sue E; La, Bonnie; Gilmartin, Allissia et al. (2010) Studies of the ""chain reversal regions"" of the avian sarcoma/leukosis virus (ASLV) and ebolavirus fusion proteins: analogous residues are important, and a His residue unique to EnvA affects the pH dependence of ASLV entry. J Virol 84:5687-94
Schornberg, Kathryn L; Shoemaker, Charles J; Dube, Derek et al. (2009) Alpha5beta1-integrin controls ebolavirus entry by regulating endosomal cathepsins. Proc Natl Acad Sci U S A 106:8003-8
Mire, Chad E; Dube, Derek; Delos, Sue E et al. (2009) Glycoprotein-dependent acidification of vesicular stomatitis virus enhances release of matrix protein. J Virol 83:12139-50
Melder, Deborah C; Yin, Xueqian; Delos, Sue E et al. (2009) A charged second-site mutation in the fusion peptide rescues replication of a mutant avian sarcoma and leukosis virus lacking critical cysteine residues flanking the internal fusion domain. J Virol 83:8575-86

Showing the most recent 10 out of 51 publications