Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI052310-02
Application #
6762423
Study Section
Immunological Sciences Study Section (IMS)
Program Officer
Johnson, David R
Project Start
2003-07-01
Project End
2006-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$303,200
Indirect Cost
Name
National Jewish Health
Department
Type
DUNS #
076443019
City
Denver
State
CO
Country
United States
Zip Code
80206
Sang, Allison; Danhorn, Thomas; Peterson, Jacob N et al. (2018) Innate and adaptive signals enhance differentiation and expansion of dual-antibody autoreactive B cells in lupus. Nat Commun 9:3973
Agazio, Amanda E; Pelanda, Roberta; Torres, Raul M (2018) Silencing of TLM B cells by chronic HIV infection. Nat Immunol 19:902-903
Greaves, Sarah A; Peterson, Jacob N; Torres, Raul M et al. (2018) Activation of the MEK-ERK Pathway Is Necessary but Not Sufficient for Breaking Central B Cell Tolerance. Front Immunol 9:707
Bednarek, Joseph; Traxinger, Brianna; Brigham, Dania et al. (2018) Cytokine-Producing B Cells Promote Immune-Mediated Bile Duct Injury in Murine Biliary Atresia. Hepatology 68:1890-1904
Schroeder, Kristin M S; Agazio, Amanda; Strauch, Pamela J et al. (2017) Breaching peripheral tolerance promotes the production of HIV-1-neutralizing antibodies. J Exp Med 214:2283-2302
Lang, Julie; Zhang, Bicheng; Kelly, Margot et al. (2017) Replacing mouse BAFF with human BAFF does not improve B-cell maturation in hematopoietic humanized mice. Blood Adv 1:2729-2741
Lang, Julie; Ota, Takayuki; Kelly, Margot et al. (2016) Receptor editing and genetic variability in human autoreactive B cells. J Exp Med 213:93-108
Hobeika, Elias; Levit-Zerdoun, Ella; Anastasopoulou, Vasiliki et al. (2015) CD19 and BAFF-R can signal to promote B-cell survival in the absence of Syk. EMBO J 34:925-39
Pelanda, Roberta (2014) Dual immunoglobulin light chain B cells: Trojan horses of autoimmunity? Curr Opin Immunol 27:53-9
Hu, Jiancheng; Oda, Shannon K; Shotts, Kristin et al. (2014) Lysophosphatidic acid receptor 5 inhibits B cell antigen receptor signaling and antibody response. J Immunol 193:85-95

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