Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA017229-14S1
Application #
3164616
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1978-12-01
Project End
1991-12-31
Budget Start
1990-03-23
Budget End
1991-12-31
Support Year
14
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Meharry Medical College
Department
Type
Schools of Medicine
DUNS #
City
Nashville
State
TN
Country
United States
Zip Code
37208
Russell, Shirley B; Russell, James D; Trupin, Kathryn M et al. (2010) Epigenetically altered wound healing in keloid fibroblasts. J Invest Dermatol 130:2489-96
Meyer, L J; Russell, S B; Russell, J D et al. (2000) Reduced hyaluronan in keloid tissue and cultured keloid fibroblasts. J Invest Dermatol 114:953-9
Russell, S B; Trupin, J S; Kennedy, R Z et al. (1995) Glucocorticoid regulation of elastin synthesis in human fibroblasts: down-regulation in fibroblasts from normal dermis but not from keloids. J Invest Dermatol 104:241-5
Myles, M E; Russell, J D; Trupin, J S et al. (1992) Keloid fibroblasts are refractory to inhibition of DNA synthesis by phorbol esters. Altered response is accompanied by reduced sensitivity to prostaglandin E2 and altered down-regulation of phorbol ester binding sites. J Biol Chem 267:9014-20
Russell, S B; Trupin, J S; Myers, J C et al. (1989) Differential glucocorticoid regulation of collagen mRNAs in human dermal fibroblasts. Keloid-derived and fetal fibroblasts are refractory to down-regulation. J Biol Chem 264:13730-5
Russell, S B; Trupin, K M; Rodriguez-Eaton, S et al. (1988) Reduced growth-factor requirement of keloid-derived fibroblasts may account for tumor growth. Proc Natl Acad Sci U S A 85:587-91