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Liyanage, Pramodha S; Walker, Alice R; Brenlla, Alfonso et al. (2017) Bulky Lesion Bypass Requires Dpo4 Binding in Distinct Conformations. Sci Rep 7:17383
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Brenlla, Alfonso; Rueda, David; Romano, Louis J (2015) Mechanism of aromatic amine carcinogen bypass by the Y-family polymerase, Dpo4. Nucleic Acids Res 43:9918-27
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Brenlla, Alfonso; Markiewicz, Radoslaw P; Rueda, David et al. (2014) Nucleotide selection by the Y-family DNA polymerase Dpo4 involves template translocation and misalignment. Nucleic Acids Res 42:2555-63
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Vrtis, Kyle B; Markiewicz, Radoslaw P; Romano, Louis J et al. (2013) Carcinogenic adducts induce distinct DNA polymerase binding orientations. Nucleic Acids Res 41:7843-53
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Markiewicz, Radoslaw P; Vrtis, Kyle B; Rueda, David et al. (2012) Single-molecule microscopy reveals new insights into nucleotide selection by DNA polymerase I. Nucleic Acids Res 40:7975-84
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Federley, Richard G; Romano, Louis J (2010) DNA polymerase: structural homology, conformational dynamics, and the effects of carcinogenic DNA adducts. J Nucleic Acids 2010:
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Vooradi, Venkataramana; Romano, Louis J (2009) Effect of N-2-acetylaminofluorene and 2-aminofluorene adducts on DNA binding and synthesis by yeast DNA polymerase eta. Biochemistry 48:4209-16
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Christian, Thomas D; Romano, Louis J; Rueda, David (2009) Single-molecule measurements of synthesis by DNA polymerase with base-pair resolution. Proc Natl Acad Sci U S A 106:21109-14
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Christian, Thomas D; Romano, Louis J (2009) Monitoring the conformation of benzo[a]pyrene adducts in the polymerase active site using fluorescence resonance energy transfer. Biochemistry 48:5382-8
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Lone, Samer; Romano, Louis J (2007) The role of specific amino acid residues in the active site of Escherichia coli DNA polymerase I on translesion DNA synthesis across from and past an N-2-aminofluorene adduct. Biochemistry 46:2599-607
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