Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA043796-16S1
Application #
6948746
Study Section
Metabolic Pathology Study Section (MEP)
Program Officer
Rosenfeld, Bobby
Project Start
1987-07-15
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
16
Fiscal Year
2004
Total Cost
$34,901
Indirect Cost
Name
Weill Medical College of Cornell University
Department
Pharmacology
Type
Schools of Medicine
DUNS #
060217502
City
New York
State
NY
Country
United States
Zip Code
10065
Laursen, Kristian B; Gudas, Lorraine J (2018) Combinatorial knockout of RAR?, RAR?, and RAR? completely abrogates transcriptional responses to retinoic acid in murine embryonic stem cells. J Biol Chem 293:11891-11900
Quintero, Cynthia M; Laursen, Kristian B; Mongan, Nigel P et al. (2018) CARM1 (PRMT4) Acts as a Transcriptional Coactivator during Retinoic Acid-Induced Embryonic Stem Cell Differentiation. J Mol Biol 430:4168-4182
Simandi, Zoltan; Horvath, Attila; Wright, Lyndsey C et al. (2016) OCT4 Acts as an Integrator of Pluripotency and Signal-Induced Differentiation. Mol Cell 63:647-661
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Trasino, S E; Tang, X-H; Jessurun, J et al. (2016) Retinoic acid receptor ?2 agonists restore glycaemic control in diabetes and reduce steatosis. Diabetes Obes Metab 18:142-51
Nilsson, Emeli M; Laursen, Kristian B; Whitchurch, Jonathan et al. (2015) MiR137 is an androgen regulated repressor of an extended network of transcriptional coregulators. Oncotarget 6:35710-25
Orfali, Nina; O'Donovan, Tracey R; Nyhan, Michelle J et al. (2015) Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulation. Exp Hematol 43:781-93.e2
Trasino, Steven E; Tang, Xiao-Han; Jessurun, Jose et al. (2015) Obesity Leads to Tissue, but not Serum Vitamin A Deficiency. Sci Rep 5:15893
Trasino, Steven E; Benoit, Yannick D; Gudas, Lorraine J (2015) Vitamin A deficiency causes hyperglycemia and loss of pancreatic ?-cell mass. J Biol Chem 290:1456-73
Laursen, Kristian B; Kashyap, Vasundhra; Scandura, Joseph et al. (2015) An alternative retinoic acid-responsive Stra6 promoter regulated in response to retinol deficiency. J Biol Chem 290:4356-66

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