HPV-18 Effects on Epithelial Cell Differentiation

Laimins, Laimonis A.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Research Project (R01)
• Project #: 3R01CA049670-05S1
• Application #: 3193897
• Study Section: Virology Study Section (VR)
• Project Start: 1989-04-01
• Project End: 1993-06-30
• Budget Start: 1993-04-01
• Budget End: 1993-06-30
• Support Year: 5
• Fiscal Year: 1993

Institution

• Name: University of Chicago
• Type: Schools of Medicine
• DUNS #: 225410919
• City: Chicago
• State: IL
• Country: United States
• Zip Code: 60637

Publications

Lechner, M S; Laimins, L A (1994) Inhibition of p53 DNA binding by human papillomavirus E6 proteins. J Virol 68:4262-73

Lechner, M S; Mack, D H; Finicle, A B et al. (1992) Human papillomavirus E6 proteins bind p53 in vivo and abrogate p53-mediated repression of transcription. EMBO J 11:3045-52

Lechner, M S; Laimins, L A (1991) Human epithelial cells immortalized by SV40 retain differentiation capabilities in an in vitro raft system and maintain viral DNA extrachromosomally. Virology 185:563-71

Bedell, M A; Hudson, J B; Golub, T R et al. (1991) Amplification of human papillomavirus genomes in vitro is dependent on epithelial differentiation. J Virol 65:2254-60

Hudson, J B; Bedell, M A; McCance, D J et al. (1990) Immortalization and altered differentiation of human keratinocytes in vitro by the E6 and E7 open reading frames of human papillomavirus type 18. J Virol 64:519-26