Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA052443-05S1
Application #
2875936
Study Section
Physiological Chemistry Study Section (PC)
Program Officer
Marks, Cheryl L
Project Start
1990-07-01
Project End
2000-11-30
Budget Start
1997-12-01
Budget End
1998-11-30
Support Year
5
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Wake Forest University Health Sciences
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
041418799
City
Winston-Salem
State
NC
Country
United States
Zip Code
27106
Lin, Hsin-Ching; Simon, Peter J; Ysla, Riza M et al. (2017) RNA stability regulates human T cell leukemia virus type 1 gene expression in chronically-infected CD4 T cells. Virology 508:7-17
Li, Mei-Ling; Weng, Kuo-Feng; Shih, Shin-Ru et al. (2016) The evolving world of small RNAs from RNA viruses. Wiley Interdiscip Rev RNA 7:575-88
Lin, Jing-Yi; Brewer, Gary; Li, Mei-Ling (2015) HuR and Ago2 Bind the Internal Ribosome Entry Site of Enterovirus 71 and Promote Virus Translation and Replication. PLoS One 10:e0140291
Lin, Jing-Yi; Li, Mei-Ling; Brewer, Gary (2014) mRNA decay factor AUF1 binds the internal ribosomal entry site of enterovirus 71 and inhibits virus replication. PLoS One 9:e103827
Kishor, Aparna; Tandukar, Bishal; Ly, Yann V et al. (2013) Hsp70 is a novel posttranscriptional regulator of gene expression that binds and stabilizes selected mRNAs containing AU-rich elements. Mol Cell Biol 33:71-84
White, Elizabeth J F; Brewer, Gary; Wilson, Gerald M (2013) Post-transcriptional control of gene expression by AUF1: mechanisms, physiological targets, and regulation. Biochim Biophys Acta 1829:680-8
Li, Mei-Ling; Defren, Jennifer; Brewer, Gary (2013) Hsp27 and F-box protein ýý-TrCP promote degradation of mRNA decay factor AUF1. Mol Cell Biol 33:2315-26
Wu, Xiangyue; Chesoni, Sandra; Rondeau, Gaelle et al. (2013) Combinatorial mRNA binding by AUF1 and Argonaute 2 controls decay of selected target mRNAs. Nucleic Acids Res 41:2644-58
Zhang, Zhuo; Qin, Yong-Wen; Brewer, Gary et al. (2012) MicroRNA degradation and turnover: regulating the regulators. Wiley Interdiscip Rev RNA 3:593-600
Qi, Mei-Yan; Wang, Zhi-Zhang; Zhang, Zhuo et al. (2012) AU-rich-element-dependent translation repression requires the cooperation of tristetraprolin and RCK/P54. Mol Cell Biol 32:913-28

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