This is a continuation of grant RO1DA07109, """"""""Developmental Effects of Prenatal Cocaine Exposure."""""""" Knowledge of the long-term consequences of prenatal exposure to cocaine is still limited by the lack of longitudinal prospective studies that follow these children out to school age. The currently funded longitudinal study (up to 30 months of age) has maintained a large sample of : 1) children exposed to cocaine: 2) to alcohol, cigarettes and/or marijuana alone; and 3) to none of these substances. This a proposal to continue to follow 307 of these subjects at 4 1/2, 5 1/2, and 7 1/2 years of age. This will permit examination of their emotional, social, and Cognitive development through the transitions to school entry and formal class work. The following questions will be addressed: 1) Does prenatal exposure to cocaine, alcohol, cigarettes, and/or marijuana, controlling for environmental and neonatal medical risk, directly affect the school-aged child's emotional and cognitive functioning?; 2) Does prenatal substance exposure interact with environmental factors to affect the school-aged child's functioning?; and 3) Is the effect of substance exposure predominately indirect, operating through mediating variables such as the child's earlier emotional regulation and environment? Answers to these questions will have implications for the most effective intervention strategies.
| Bennett, David S; Birnkrant, Jennifer M; Carmody, Dennis P et al. (2015) Effects of prenatal cocaine exposure on pubertal development. Neurotoxicol Teratol 47:146-53 |
| Allen, Jedediah W P; Bennett, David S; Carmody, Dennis P et al. (2014) Adolescent risk-taking as a function of prenatal cocaine exposure and biological sex. Neurotoxicol Teratol 41:65-70 |
| Bennett, David S; Mohamed, Feroze B; Carmody, Dennis P et al. (2013) Prenatal tobacco exposure predicts differential brain function during working memory in early adolescence: a preliminary investigation. Brain Imaging Behav 7:49-59 |
| Bennett, David S; Marini, Victoria A; Berzenski, Sara R et al. (2013) Externalizing problems in late childhood as a function of prenatal cocaine exposure and environmental risk. J Pediatr Psychol 38:296-308 |
| Carmody, Dennis P; Bennett, David S; Lewis, Michael (2011) The effects of prenatal cocaine exposure and gender on inhibitory control and attention. Neurotoxicol Teratol 33:61-8 |
| Bennett, David S; Mohamed, Feroze B; Carmody, Dennis P et al. (2009) Response inhibition among early adolescents prenatally exposed to tobacco: an fMRI study. Neurotoxicol Teratol 31:283-90 |
| Bennett, David S; Bendersky, Margaret; Lewis, Michael (2008) Children's cognitive ability from 4 to 9 years old as a function of prenatal cocaine exposure, environmental risk, and maternal verbal intelligence. Dev Psychol 44:919-28 |
| Bennett, David; Bendersky, Margaret; Lewis, Michael (2007) Preadolescent health risk behavior as a function of prenatal cocaine exposure and gender. J Dev Behav Pediatr 28:467-72 |
| Carmody, Dennis P; Moreno, Rosanne; Mars, Audrey E et al. (2007) Brief report: brain activation to social words in a sedated child with autism. J Autism Dev Disord 37:1381-5 |
| Dennis, Tracy; Bendersky, Margaret; Ramsay, Douglas et al. (2006) Reactivity and regulation in children prenatally exposed to cocaine. Dev Psychol 42:688-97 |
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