Despite the success of treating dentofacial deformities using orthodontics and surgery, some types of deformities still cannot be corrected with predictable results, long-term stability, and patient satisfaction. The goals of this proposal are to delineate the risk factors associated with long term instability after treatment, and to clarify the ultimate outcomes of the treatment of dentofacial deformity, using and enlarging the extensive University of North Carolina database. Data on the long-term skeletal and dental changes and the patients evaluation of these changes will be examined for three purposes: (1) to more clearly differentiate the patient-perceived and objective outcomes of orthognathic surgery vs. Orthodontics alone in the treatment of dentofacial deformity; (2) to place both short- and long-term risks of both types of treatment in perspective so that patients can make more informed choices between alternative approaches; and (3) to clarify the circumstances in orthognathic surgery that allow outpatient (day-op) care as opposed to inpatient hospitalization by evaluating both the objective and patient perceived experience and adverse events that occur in each of these settings.

National Institute of Health (NIH)
National Institute of Dental & Craniofacial Research (NIDCR)
Research Project (R01)
Project #
Application #
Study Section
Special Emphasis Panel (ZDE1 (24))
Program Officer
Fischer, Dena
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of North Carolina Chapel Hill
Schools of Dentistry
Chapel Hill
United States
Zip Code
Brookes, Carolyn Dicus; Berry, John; Rich, Josiah et al. (2015) Multimodal protocol reduces postoperative nausea and vomiting in patients undergoing Le Fort I osteotomy. J Oral Maxillofac Surg 73:324-32
Brookes, Carolyn Dicus; Turvey, Timothy A; Phillips, Ceib et al. (2015) Postdischarge Nausea and Vomiting Remains Frequent After Le Fort I Osteotomy Despite Implementation of a Multimodal Antiemetic Protocol Effective in Reducing Postoperative Nausea and Vomiting. J Oral Maxillofac Surg 73:1259-66
Phillips, C; Brookes, C D; Rich, J et al. (2015) Postoperative nausea and vomiting following orthognathic surgery. Int J Oral Maxillofac Surg 44:745-51
Brookes, Carolyn Dicus; Golden, Brent A; Lawrence, Scott D et al. (2015) Unilateral mydriasis after maxillary osteotomy: a case series and review of the literature. J Oral Maxillofac Surg 73:1159-68
Magraw, Caitlin B L; Garaas, Rachel; Shaw, Alan et al. (2015) Changes in scleral exposure following modified Le Fort III osteotomy. Oral Surg Oral Med Oral Pathol Oral Radiol 120:119-24.e1
Nguyen, Tung; Cevidanes, Lucia; Paniagua, Beatriz et al. (2014) Use of shape correspondence analysis to quantify skeletal changes associated with bone-anchored Class III correction. Angle Orthod 84:329-36
Perin, J; Preisser, J S; Phillips, C et al. (2014) Regression analysis of correlated ordinal data using orthogonalized residuals. Biometrics 70:902-9
Blakey, G H; Rossouw, E; Turvey, T A et al. (2014) Are bioresorbable polylactate devices comparable to titanium devices for stabilizing Le Fort I advancement? Int J Oral Maxillofac Surg 43:437-44
Rich, J; Golden, B A; Phillips, C (2014) Systematic review of preoperative mandibular canal position as it relates to postoperative neurosensory disturbance following the sagittal split ramus osteotomy. Int J Oral Maxillofac Surg 43:1076-81
Scheffler, Nicole R; Proffit, William R; Phillips, Ceib (2014) Outcomes and stability in patients with anterior open bite and long anterior face height treated with temporary anchorage devices and a maxillary intrusion splint. Am J Orthod Dentofacial Orthop 146:594-602

Showing the most recent 10 out of 76 publications