Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
3R01DE009569-06S1
Application #
2130629
Study Section
AIDS and Related Research Study Section 4 (ARRD)
Project Start
1990-06-04
Project End
1997-08-14
Budget Start
1995-08-15
Budget End
1996-08-14
Support Year
6
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Biochemistry
Type
Schools of Dentistry
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Hodinka, R L; Nagashunmugam, T; Malamud, D (1998) Detection of human immunodeficiency virus antibodies in oral fluids. Clin Diagn Lab Immunol 5:419-26
Kennedy, S; Davis, C; Abrams, W R et al. (1998) Submandibular salivary proteases: lack of a role in anti-HIV activity. J Dent Res 77:1515-9
Nagashunmugam, T; Malamud, D; Davis, C et al. (1998) Human submandibular saliva inhibits human immunodeficiency virus type 1 infection by displacing envelope glycoprotein gp120 from the virus. J Infect Dis 178:1635-41
Taichman, N S; Cruchley, A T; Fletcher, L M et al. (1998) Vascular endothelial growth factor in normal human salivary glands and saliva: a possible role in the maintenance of mucosal homeostasis. Lab Invest 78:869-75
Malamud, D; Nagashunmugam, T; Davis, C et al. (1997) Inhibition of HIV infectivity by human saliva. Oral Dis 3 Suppl 1:S58-63
Nagashunmugam, T; Friedman, H M; Davis, C et al. (1997) Human submandibular saliva specifically inhibits HIV type 1. AIDS Res Hum Retroviruses 13:371-6
Nagashunmugam, T; Friedman, H M (1996) Cell-free HIV-1Zr6 vif mutants are defective in binding to peripheral blood mononuclear cells and in internalization. DNA Cell Biol 15:353-61
Chehimi, J; Ma, X; Chouaib, S et al. (1996) Differential production of interleukin 10 during human immunodeficiency virus infection. AIDS Res Hum Retroviruses 12:1141-9
Pearce-Pratt, R; Malamud, D; Phillips, D M (1994) Role of the cytoskeleton in cell-to-cell transmission of human immunodeficiency virus. J Virol 68:2898-905
Malamud, D; Friedman, H M (1993) HIV in the oral cavity: virus, viral inhibitory activity, and antiviral antibodies: a review. Crit Rev Oral Biol Med 4:461-6

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