Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
5R01DE010132-06
Application #
2131088
Study Section
Oral Biology and Medicine Subcommittee 1 (OBM)
Project Start
1991-07-01
Project End
1998-09-29
Budget Start
1996-09-30
Budget End
1997-09-29
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Maryland Baltimore
Department
Physiology
Type
Schools of Dentistry
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Dessem, Dean (2011) Physiological, morphological and neurochemical characterization of neurons modulated by movement. J Vis Exp :
Dessem, Dean; Ambalavanar, Ranjinidevi; Evancho, Melena et al. (2010) Eccentric muscle contraction and stretching evoke mechanical hyperalgesia and modulate CGRP and P2X(3) expression in a functionally relevant manner. Pain 149:284-95
Ambalavanar, R; Dessem, D (2009) Emerging peripheral receptor targets for deep-tissue craniofacial pain therapies. J Dent Res 88:201-11
Ambalavanar, R; Yallampalli, C; Yallampalli, U et al. (2007) Injection of adjuvant but not acidic saline into craniofacial muscle evokes nociceptive behaviors and neuropeptide expression. Neuroscience 149:650-9
Dessem, Dean; Moritani, Masayuki; Ambalavanar, Ranjinidevi (2007) Nociceptive craniofacial muscle primary afferent neurons synapse in both the rostral and caudal brain stem. J Neurophysiol 98:214-23
Ambalavanar, Ranjinidevi; Moutanni, Aicha; Dessem, Dean (2006) Inflammation of craniofacial muscle induces widespread mechanical allodynia. Neurosci Lett 399:249-54
Masri, Radi; Ro, Jin Y; Dessem, Dean et al. (2006) Classification of muscle spindle afferents innervating the masseter muscle in rats. Arch Oral Biol 51:740-7
Ambalavanar, Ranjinidevi; Moritani, Masayuki; Moutanni, Aicha et al. (2006) Deep tissue inflammation upregulates neuropeptides and evokes nociceptive behaviors which are modulated by a neuropeptide antagonist. Pain 120:53-68
Ambalavanar, R; Dessem, D; Moutanni, A et al. (2006) Muscle inflammation induces a rapid increase in calcitonin gene-related peptide (CGRP) mRNA that temporally relates to CGRP immunoreactivity and nociceptive behavior. Neuroscience 143:875-84
Ambalavanar, Ranjinidevi; Moritani, Masayuki; Dessem, Dean (2005) Trigeminal P2X3 receptor expression differs from dorsal root ganglion and is modulated by deep tissue inflammation. Pain 117:280-91

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