Rohatgi, Nidhi; Aly, Haytham; Marshall, Connie A et al. (2013) Novel insulin sensitizer modulates nutrient sensing pathways and maintains ýý-cell phenotype in human islets. PLoS One 8:e62012
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Aly, Haytham; Rohatgi, Nidhi; Marshall, Connie A et al. (2013) A novel strategy to increase the proliferative potential of adult human ?-cells while maintaining their differentiated phenotype. PLoS One 8:e66131
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Vernier, Stephanie; Chiu, Angela; Schober, Joseph et al. (2012) ?-cell metabolic alterations under chronic nutrient overload in rat and human islets. Islets 4:379-92
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Rohatgi, Nidhi; Remedi, Maria S; Kwon, Guim et al. (2010) Therapeutic Strategies to Increase Human ?-Cell Growth and Proliferation by Regulating mTOR and GSK-3/?-Catenin Pathways. Open Endocrinol J 4:
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Liu, Hui; Remedi, Maria S; Pappan, Kirk L et al. (2009) Glycogen synthase kinase-3 and mammalian target of rapamycin pathways contribute to DNA synthesis, cell cycle progression, and proliferation in human islets. Diabetes 58:663-72
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Kwon, Guim; Marshall, Connie A; Liu, Hui et al. (2006) Glucose-stimulated DNA synthesis through mammalian target of rapamycin (mTOR) is regulated by KATP channels: effects on cell cycle progression in rodent islets. J Biol Chem 281:3261-7
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Pappan, Kirk L; Pan, Zhijun; Kwon, Guim et al. (2005) Pancreatic beta-cell lipoprotein lipase independently regulates islet glucose metabolism and normal insulin secretion. J Biol Chem 280:9023-9
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Kwon, Guim; Pappan, Kirk L; Marshall, Connie A et al. (2004) cAMP Dose-dependently prevents palmitate-induced apoptosis by both protein kinase A- and cAMP-guanine nucleotide exchange factor-dependent pathways in beta-cells. J Biol Chem 279:8938-45
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Cruz, W S; Kwon, G; Marshall, C A et al. (2001) Glucose and insulin stimulate heparin-releasable lipoprotein lipase activity in mouse islets and INS-1 cells. A potential link between insulin resistance and beta-cell dysfunction. J Biol Chem 276:12162-8
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Hill, J R; Kwon, G; Marshall, C A et al. (1998) Hyperglycemic levels of glucose inhibit interleukin 1 release from RAW 264.7 murine macrophages by activation of protein kinase C. J Biol Chem 273:3308-13
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