Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK016105-23
Application #
2136984
Study Section
General Medicine B Study Section (GMB)
Project Start
1975-01-01
Project End
1997-12-31
Budget Start
1995-05-01
Budget End
1997-12-31
Support Year
23
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
City
Rochester
State
MN
Country
United States
Zip Code
55905
Dogan, Soner; Johannsen, Anna C; Grande, Joseph P et al. (2011) Effects of intermittent and chronic calorie restriction on mammalian target of rapamycin (mTOR) and IGF-I signaling pathways in mammary fat pad tissues and mammary tumors. Nutr Cancer 63:389-401
Rogozina, Olga P; Bonorden, Melissa J L; Grande, Joseph P et al. (2009) Serum insulin-like growth factor-I and mammary tumor development in ad libitum-fed, chronic calorie-restricted, and intermittent calorie-restricted MMTV-TGF-alpha mice. Cancer Prev Res (Phila Pa) 2:712-9
Cheng, Jingfei; Zhou, Wei; Warner, Gina M et al. (2009) Temporal analysis of signaling pathways activated in a murine model of two-kidney, one-clip hypertension. Am J Physiol Renal Physiol 297:F1055-68
Diaz Encarnacion, Montserrat M; Warner, Gina M; Gray, Catherine E et al. (2008) Signaling pathways modulated by fish oil in salt-sensitive hypertension. Am J Physiol Renal Physiol 294:F1323-35
Dogan, Soner; Hu, Xin; Zhang, Yan et al. (2007) Effects of high-fat diet and/or body weight on mammary tumor leptin and apoptosis signaling pathways in MMTV-TGF-alpha mice. Breast Cancer Res 9:R91
Tracz, Michal J; Juncos, Julio P; Grande, Joseph P et al. (2007) Renal hemodynamic, inflammatory, and apoptotic responses to lipopolysaccharide in HO-1-/- mice. Am J Pathol 170:1820-30
Murali, Narayana S; Ackerman, Allan W; Croatt, Anthony J et al. (2007) Renal upregulation of HO-1 reduces albumin-driven MCP-1 production: implications for chronic kidney disease. Am J Physiol Renal Physiol 292:F837-44
Cheng, Jingfei; Grande, Joseph P (2007) Cyclic nucleotide phosphodiesterase (PDE) inhibitors: novel therapeutic agents for progressive renal disease. Exp Biol Med (Maywood) 232:38-51
Cleary, Margot P; Hu, Xin; Grossmann, Michael E et al. (2007) Prevention of mammary tumorigenesis by intermittent caloric restriction: does caloric intake during refeeding modulate the response? Exp Biol Med (Maywood) 232:70-80
Cheng, Jingfei; Thompson, Michael A; Walker, Henry J et al. (2006) Lixazinone stimulates mitogenesis of Madin-Darby canine kidney cells. Exp Biol Med (Maywood) 231:288-95

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