Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK037482-03
Application #
3236423
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1987-05-01
Project End
1991-04-30
Budget Start
1989-05-01
Budget End
1991-04-30
Support Year
3
Fiscal Year
1989
Total Cost
Indirect Cost
Name
University of Texas Health Science Center San Antonio
Department
Type
School of Medicine & Dentistry
DUNS #
800772162
City
San Antonio
State
TX
Country
United States
Zip Code
78229
Criddle, David N; Booth, David M; Mukherjee, Rajarshi et al. (2009) Cholecystokinin-58 and cholecystokinin-8 exhibit similar actions on calcium signaling, zymogen secretion, and cell fate in murine pancreatic acinar cells. Am J Physiol Gastrointest Liver Physiol 297:G1085-92
Murphy, John A; Criddle, David N; Sherwood, Mark et al. (2008) Direct activation of cytosolic Ca2+ signaling and enzyme secretion by cholecystokinin in human pancreatic acinar cells. Gastroenterology 135:632-41
Yamamoto, Mitsuyoshi; Reeve Jr, Joseph R; Green, Gary M (2007) Supramaximal CCK-58 does not induce pancreatitis in the rat: role of pancreatic water secretion. Am J Physiol Gastrointest Liver Physiol 292:G964-74
Yamamoto, M; Reeve Jr, J R; Keire, D A et al. (2005) Water and enzyme secretion are tightly coupled in pancreatic secretion stimulated by food or CCK-58 but not by CCK-8. Am J Physiol Gastrointest Liver Physiol 288:G866-79
Reeve Jr, Joseph R; Liddle, Rodger A; McVey, Douglas C et al. (2004) Identification of nonsulfated cholecystokinin-58 in canine intestinal extracts and its biological properties. Am J Physiol Gastrointest Liver Physiol 287:G326-33
Reeve Jr, Joseph R; Keire, David A; Coskun, Tamer et al. (2003) Synthesis of biologically active canine CCK-58. Regul Pept 113:71-7
Jin, Wei; Green, Gary M (2003) Circulating ethanol does not stimulate pancreatic secretion in conscious rats. Pancreas 27:e90-5
Reeve Jr, Joseph R; Green, Gary M; Chew, Peter et al. (2003) CCK-58 is the only detectable endocrine form of cholecystokinin in rat. Am J Physiol Gastrointest Liver Physiol 285:G255-65
Wang, Yu; Prpic, Vera; Green, Gary M et al. (2002) Luminal CCK-releasing factor stimulates CCK release from human intestinal endocrine and STC-1 cells. Am J Physiol Gastrointest Liver Physiol 282:G16-22
Spannagel, A W; Green, G M (1999) Pancreatic hypersecretion in the jejunal-bypass rat. Pancreas 18:47-52

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