Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
2R01DK041122-10A2
Application #
6266836
Study Section
General Medicine A Subcommittee 2 (GMA)
Program Officer
Serrano, Jose
Project Start
1989-01-01
Project End
2005-11-30
Budget Start
2001-02-01
Budget End
2001-11-30
Support Year
10
Fiscal Year
2001
Total Cost
$294,146
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Physiology
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Muili, Kamaldeen A; Wang, Dong; Orabi, Abrahim I et al. (2013) Bile acids induce pancreatic acinar cell injury and pancreatitis by activating calcineurin. J Biol Chem 288:570-80
Sabbatini, Maria E; D'Alecy, Louis; Lentz, Stephen I et al. (2013) Adenylyl cyclase 6 mediates the action of cyclic AMP-dependent secretagogues in mouse pancreatic exocrine cells via protein kinase A pathway activation. J Physiol 591:3693-707
Sabbatini, Maria E; Bi, Yan; Ji, Baoan et al. (2010) CCK activates RhoA and Rac1 differentially through Galpha13 and Galphaq in mouse pancreatic acini. Am J Physiol Cell Physiol 298:C592-601
Lee, SaeHong; Wishart, Matthew J; Williams, John A (2009) Identification of calcineurin regulated phosphorylation sites on CRHSP-24. Biochem Biophys Res Commun 385:413-7
Chen, Xuequn; Andrews, Philip C (2009) Quantitative proteomics analysis of pancreatic zymogen granule membrane proteins. Methods Mol Biol 528:327-38
Williams, John A; Chen, Xuequn; Sabbatini, Maria E (2009) Small G proteins as key regulators of pancreatic digestive enzyme secretion. Am J Physiol Endocrinol Metab 296:E405-14
Chen, Xuequn; Andrews, Philip C (2008) Purification and proteomics analysis of pancreatic zymogen granule membranes. Methods Mol Biol 432:275-87
Chen, Xuequn; Walker, Angela K; Strahler, John R et al. (2006) Organellar proteomics: analysis of pancreatic zymogen granule membranes. Mol Cell Proteomics 5:306-12
Bi, Yan; Williams, John A (2005) A role for Rho and Rac in secretagogue-induced amylase release by pancreatic acini. Am J Physiol Cell Physiol 289:C22-32
Bi, Yan; Page, Sophie Le; Williams, John A (2005) Rho and Rac promote acinar morphological changes, actin reorganization, and amylase secretion. Am J Physiol Gastrointest Liver Physiol 289:G561-70

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