Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK041230-08
Application #
2141652
Study Section
Metabolism Study Section (MET)
Project Start
1989-05-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Yale University
Department
Type
Schools of Nursing
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Mamillapalli, Ramanaiah; VanHouten, Joshua; Zawalich, Walter et al. (2008) Switching of G-protein usage by the calcium-sensing receptor reverses its effect on parathyroid hormone-related protein secretion in normal versus malignant breast cells. J Biol Chem 283:24435-47
Zawalich, Walter S; Zawalich, Kathleen C (2008) Enhanced activation of phospholipase C and insulin secretion from islets incubated in fatty acid-free bovine serum albumin. Metabolism 57:290-8
Zawalich, Walter S; Yamazaki, Hanae; Zawalich, Kathleen C (2008) Biphasic insulin secretion from freshly isolated or cultured, perifused rodent islets: comparative studies with rats and mice. Metabolism 57:30-9
Li, Yanyan; Wang, Peili; Xu, Jianchao et al. (2007) Regulation of insulin secretion and GLUT4 trafficking by the calcium sensor synaptotagmin VII. Biochem Biophys Res Commun 362:658-64
Zawalich, Walter S; Zawalich, Kathleen C; Yamazaki, Hanae (2007) Divergent effects of epinephrine and prostaglandin E2 on glucose-induced insulin secretion from perifused rat islets. Metabolism 56:12-8
Zawalich, Walter S; Tesz, Gregory J; Yamazaki, Hanae et al. (2006) Dexamethasone suppresses phospholipase C activation and insulin secretion from isolated rat islets. Metabolism 55:35-42
Yamazaki, Hanae; Philbrick, William; Zawalich, Kathleen C et al. (2006) Acute and chronic effects of glucose and carbachol on insulin secretion and phospholipase C activation: studies with diazoxide and atropine. Am J Physiol Endocrinol Metab 290:E26-E33
Zhu, Yong Lian; Abdo, Alexander; Gesmonde, Joan F et al. (2004) Aggregation and lack of secretion of most newly synthesized proinsulin in non-beta-cell lines. Endocrinology 145:3840-9
Zawalich, Walter S; Zawalich, Kathleen C; Tesz, Gregory J et al. (2004) Effects of muscarinic receptor type 3 knockout on mouse islet secretory responses. Biochem Biophys Res Commun 315:872-6
Geisler, John G; Zawalich, Walter; Zawalich, Kathleen et al. (2002) Estrogen can prevent or reverse obesity and diabetes in mice expressing human islet amyloid polypeptide. Diabetes 51:2158-69

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