Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
1R01DK052208-01
Application #
2017738
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1997-01-01
Project End
2000-12-31
Budget Start
1997-01-01
Budget End
1997-12-31
Support Year
1
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Sloan-Kettering Institute for Cancer Research
Department
Type
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10065
Asai, Takashi; Hatlen, Megan A; Lossos, Chen et al. (2016) Generation of a novel, multi-stage, progressive, and transplantable model of plasma cell neoplasms. Sci Rep 6:22760
Asai, Takashi; Liu, Yan; Di Giandomenico, Silvana et al. (2012) Necdin, a p53 target gene, regulates the quiescence and response to genotoxic stress of hematopoietic stem/progenitor cells. Blood 120:1601-12
Bazzoli, Elena; Pulvirenti, Teodoro; Oberstadt, Moritz C et al. (2012) MEF promotes stemness in the pathogenesis of gliomas. Cell Stem Cell 11:836-44
Xu, Haiming; Menendez, Silvia; Schlegelberger, Brigitte et al. (2012) Loss of p53 accelerates the complications of myelodysplastic syndrome in a NUP98-HOXD13-driven mouse model. Blood 120:3089-97
Liu, Yan; Liu, Fan; Yu, Hao et al. (2012) Akt phosphorylates the transcriptional repressor bmi1 to block its effects on the tumor-suppressing ink4a-arf locus. Sci Signal 5:ra77
Huang, Gang; Zhao, Xinghui; Wang, Lan et al. (2011) The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations. Blood 118:6544-52
Asai, Takashi; Liu, Yan; Bae, Narae et al. (2011) The p53 tumor suppressor protein regulates hematopoietic stem cell fate. J Cell Physiol 226:2215-21
Sashida, Goro; Bae, Narae; Di Giandomenico, Silvana et al. (2011) The mef/elf4 transcription factor fine tunes the DNA damage response. Cancer Res 71:4857-65
Sashida, Goro; Bazzoli, Elena; Menendez, Silvia et al. (2010) The oncogenic role of the ETS transcription factors MEF and ERG. Cell Cycle 9:3457-9
Miyata, Yasuhiko; Liu, Yan; Jankovic, Vladimir et al. (2010) Cyclin C regulates human hematopoietic stem/progenitor cell quiescence. Stem Cells 28:308-17

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