Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES005233-12
Application #
6637182
Study Section
Alcohol and Toxicology Subcommittee 4 (ALTX)
Program Officer
Heindel, Jerrold
Project Start
1990-08-09
Project End
2006-07-31
Budget Start
2003-08-01
Budget End
2004-07-31
Support Year
12
Fiscal Year
2003
Total Cost
$267,539
Indirect Cost
Name
University of California Davis
Department
Public Health & Prev Medicine
Type
Organized Research Units
DUNS #
047120084
City
Davis
State
CA
Country
United States
Zip Code
95618
Sciullo, Eric M; Vogel, Christoph F; Wu, Dalei et al. (2010) Effects of selected food phytochemicals in reducing the toxic actions of TCDD and p,p'-DDT in U937 macrophages. Arch Toxicol 84:957-66
Dong, Bin; Nishimura, Noriko; Vogel, Christoph F et al. (2010) TCDD-induced cyclooxygenase-2 expression is mediated by the nongenomic pathway in mouse MMDD1 macula densa cells and kidneys. Biochem Pharmacol 79:487-97
Li, Wen; Vogel, Christoph F A; Wu, Dalei et al. (2010) Non-genomic action of TCDD to induce inflammatory responses in HepG2 human hepatoma cells and in liver of C57BL/6J mice. Biol Chem 391:1205-19
Dong, Bin; Matsumura, Fumio (2009) The conversion of rapid TCCD nongenomic signals to persistent inflammatory effects via select protein kinases in MCF10A cells. Mol Endocrinol 23:549-58
Wong, Patrick S; Li, Wen; Vogel, Christoph F et al. (2009) Characterization of MCF mammary epithelial cells overexpressing the Arylhydrocarbon receptor (AhR). BMC Cancer 9:234
Vogel, Christoph F A; Matsumura, Fumio (2009) A new cross-talk between the aryl hydrocarbon receptor and RelB, a member of the NF-kappaB family. Biochem Pharmacol 77:734-45
Sciullo, Eric M; Dong, Bin; Vogel, Chris F A et al. (2009) Characterization of the pattern of the nongenomic signaling pathway through which TCDD-induces early inflammatory responses in U937 human macrophages. Chemosphere 74:1531-7
Matsumura, Fumio (2009) The significance of the nongenomic pathway in mediating inflammatory signaling of the dioxin-activated Ah receptor to cause toxic effects. Biochem Pharmacol 77:608-26
Vogel, Christoph F A; Goth, Samuel R; Dong, Bin et al. (2008) Aryl hydrocarbon receptor signaling mediates expression of indoleamine 2,3-dioxygenase. Biochem Biophys Res Commun 375:331-5
Li, Wen; Matsumura, Fumio (2008) Significance of the nongenomic, inflammatory pathway in mediating the toxic action of TCDD to induce rapid and long-term cellular responses in 3T3-L1 adipocytes. Biochemistry 47:13997-4008

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