Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
2R01EY000983-24
Application #
2019384
Study Section
Special Emphasis Panel (ZRG3-BBCA (01))
Project Start
1977-04-01
Project End
2001-09-29
Budget Start
1996-09-30
Budget End
1997-09-29
Support Year
24
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Santa Cruz
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
City
Santa Cruz
State
CA
Country
United States
Zip Code
95064
Szundi, Istvan; Funatogawa, Chie; Guo, Ying et al. (2017) Protein Sequence and Membrane Lipid Roles in the Activation Kinetics of Bovine and Human Rhodopsins. Biophys J 113:1934-1944
Szundi, Istvan; Funatogawa, Chie; Kliger, David S (2016) Complexity of Bovine Rhodopsin Activation Revealed at Low Temperature and Alkaline pH. Biochemistry 55:5095-105
Szundi, Istvan; Li, Hai; Chen, Eefei et al. (2015) Platymonas subcordiformis Channelrhodopsin-2 Function: I. THE PHOTOCHEMICAL REACTION CYCLE. J Biol Chem 290:16573-84
Szundi, Istvan; Bogomolni, Roberto; Kliger, David S (2015) Platymonas subcordiformis Channelrhodopsin-2 (PsChR2) Function: II. RELATIONSHIP OF THE PHOTOCHEMICAL REACTION CYCLE TO CHANNEL CURRENTS. J Biol Chem 290:16585-94
Mooney, Victoria L; Szundi, Istvan; Lewis, James W et al. (2012) Schiff base protonation changes in Siberian hamster ultraviolet cone pigment photointermediates. Biochemistry 51:2630-7
Kliger, David S; Chen, Eefei; Goldbeck, Robert A (2012) Probing kinetic mechanisms of protein function and folding with time-resolved natural and magnetic chiroptical spectroscopies. Int J Mol Sci 13:683-97
Tsukamoto, Hisao; Szundi, Istvan; Lewis, James W et al. (2011) Rhodopsin in nanodiscs has native membrane-like photointermediates. Biochemistry 50:5086-91
Chen, Eefei; Goldbeck, Robert A; Kliger, David S (2010) Nanosecond time-resolved polarization spectroscopies: tools for probing protein reaction mechanisms. Methods 52:3-11
Szundi, Istvan; Epps, Jacqueline; Lewis, James W et al. (2010) Temperature dependence of the lumirhodopsin I-lumirhodopsin II equilibrium. Biochemistry 49:5852-8
Thomas, Yiren Gu; Szundi, Istvan; Lewis, James W et al. (2009) Microsecond time-resolved circular dichroism of rhodopsin photointermediates. Biochemistry 48:12283-9

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