Abstract

Studies will continue of the effect of epidermal growth factor for promoting the healing of corneal endothelium. Primate studies will be done and ultra-structural analyses made. Long-term follow-up will be made of human and animals undergoing the epikeratophakia procedure. This will include the study of the repopulation of the donor """"""""living contact lens"""""""" and the study of host corneas in cases where the donor must be removed. Immunological studies of the cornea will continue with tests of cyclosporin A to prevent corneal graft rejection.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY002580-09
Application #
3256896
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1978-01-01
Project End
1987-12-31
Budget Start
1986-01-01
Budget End
1986-12-31
Support Year
9
Fiscal Year
1986
Total Cost
Indirect Cost

  Institution

Name
Louisiana State University Hsc New Orleans
Department
Type
Schools of Medicine
DUNS #
782627814
City
New Orleans
State
LA
Country
United States
Zip Code
70112

  Publications

Chiou, A G; Kaufman, S C; Beuerman, R W et al. (1999) Confocal microscopy in cornea guttata and Fuchs' endothelial dystrophy. Br J Ophthalmol 83:185-9
Chiou, A G; Kaufman, S C; Beuerman, R W et al. (1999) Confocal microscopy in the iridocorneal endothelial syndrome. Br J Ophthalmol 83:697-702
Gebhardt, B M; Hodkin, M; Varnell, E D et al. (1999) Protection of corneal allografts by CTLA4-Ig. Cornea 18:314-20
Chiou, A G; Kaufman, S C; Beuerman, R W et al. (1999) Confocal microscopy in posterior polymorphous corneal dystrophy. Ophthalmologica 213:211-3
Chiou, A G; Beuerman, R W; Kaufman, S C et al. (1999) Confocal microscopy in lattice corneal dystrophy. Graefes Arch Clin Exp Ophthalmol 237:697-701
Gebhardt, B M; Varnell, E D; Kaufman, H E (1999) Prolonged survival of corneal allografts incubated in alloantibody fragments. Transplantation 67:594-9
Chiou, A G; Kaufman, S C; Kaz, K et al. (1999) Characterization of epithelial downgrowth by confocal microscopy. J Cataract Refract Surg 25:1172-4
Chiou, A G; Kaufman, S C; Beuerman, R W et al. (1999) A confocal microscopic study of advancing wavelike epitheliopathy. Arch Ophthalmol 117:126-7
Chiou, A G; Kaufman, S C; Beuerman, R W et al. (1999) Differential diagnosis of linear corneal images on confocal microscopy. Cornea 18:63-6
Bovelle, R; Kaufman, S C; Thompson, H W et al. (1999) Corneal thickness measurements with the Topcon SP-2000P specular microscope and an ultrasound pachymeter. Arch Ophthalmol 117:868-70

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