Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY007564-11
Application #
6329512
Study Section
Visual Sciences A Study Section (VISA)
Program Officer
Fisher, Richard S
Project Start
1988-04-01
Project End
2003-11-30
Budget Start
2000-12-01
Budget End
2001-11-30
Support Year
11
Fiscal Year
2001
Total Cost
$248,969
Indirect Cost
Name
University of South Alabama
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
City
Mobile
State
AL
Country
United States
Zip Code
36688
Molesworth-Kenyon, Sara J; Milam, Ashley; Rockette, Amanda et al. (2015) Expression, Inducers and Cellular Sources of the Chemokine MIG (CXCL 9), During Primary Herpes Simplex Virus Type-1 Infection of the Cornea. Curr Eye Res 40:800-8
Molesworth-Kenyon, Sara; Mates, Aaron; Yin, Rong et al. (2005) CXCR3, IP-10, and Mig are required for CD4+ T cell recruitment during the DTH response to HSV-1 yet are independent of the mechanism for viral clearance. Virology 333:1-9
Molesworth-Kenyon, S J; Oakes, J E; Lausch, R N (2005) A novel role for neutrophils as a source of T cell-recruiting chemokines IP-10 and Mig during the DTH response to HSV-1 antigen. J Leukoc Biol 77:552-9
Fenton, Robin R; Molesworth-Kenyon, Sara; Oakes, John E et al. (2002) Linkage of IL-6 with neutrophil chemoattractant expression in virus-induced ocular inflammation. Invest Ophthalmol Vis Sci 43:737-43
Tumpey, Terrence M; Fenton, Robin; Molesworth-Kenyon, Sara et al. (2002) Role for macrophage inflammatory protein 2 (MIP-2), MIP-1alpha, and interleukin-1alpha in the delayed-type hypersensitivity response to viral antigen. J Virol 76:8050-7
Yan, X T; Zhuang, M; Oakes, J E et al. (2001) Autocrine action of IL-10 suppresses proinflammatory mediators and inflammation in the HSV-1-infected cornea. J Leukoc Biol 69:149-57
Tumpey, T M; Cheng, H; Yan, X T et al. (1998) Chemokine synthesis in the HSV-1-infected cornea and its suppression by interleukin-10. J Leukoc Biol 63:486-92
Yan, X T; Tumpey, T M; Kunkel, S L et al. (1998) Role of MIP-2 in neutrophil migration and tissue injury in the herpes simplex virus-1-infected cornea. Invest Ophthalmol Vis Sci 39:1854-62
Tumpey, T M; Cheng, H; Cook, D N et al. (1998) Absence of macrophage inflammatory protein-1alpha prevents the development of blinding herpes stromal keratitis. J Virol 72:3705-10
Lausch, R N; Chen, S H; Tumpey, T M et al. (1996) Early cytokine synthesis in the excised mouse cornea. J Interferon Cytokine Res 16:35-40

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