Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY007883-08
Application #
2161747
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1988-12-01
Project End
1997-02-28
Budget Start
1995-07-01
Budget End
1997-02-28
Support Year
8
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Florida
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
073130411
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Akin, Debra; Newman, Jeremy R B; McIntyre, Lauren M et al. (2016) RNA-seq analysis of impact of PNN on gene expression and alternative splicing in corneal epithelial cells. Mol Vis 22:40-60
Joo, Jeong Hoon; Ryu, Danny; Peng, Qian et al. (2014) Role of Pnn in alternative splicing of a specific subset of lncRNAs of the corneal epithelium. Mol Vis 20:1629-42
Joo, Jeong-Hoon; Correia, Greg P; Li, Jian-Liang et al. (2013) Transcriptomic analysis of PNN- and ESRP1-regulated alternative pre-mRNA splicing in human corneal epithelial cells. Invest Ophthalmol Vis Sci 54:697-707
Xu, Yufei; Xu, Chao; Kato, Akiko et al. (2012) Tet3 CXXC domain and dioxygenase activity cooperatively regulate key genes for Xenopus eye and neural development. Cell 151:1200-13
Joo, Jeong-Hoon; Kim, Yong H; Dunn, Nicholas W et al. (2010) Disruption of mouse corneal epithelial differentiation by conditional inactivation of pnn. Invest Ophthalmol Vis Sci 51:1927-34
Joo, Jeong-Hoon; Taxter, Timothy J; Munguba, Gustavo C et al. (2010) Pinin modulates expression of an intestinal homeobox gene, Cdx2, and plays an essential role for small intestinal morphogenesis. Dev Biol 345:191-203
Alpatov, Roman; Shi, Yujiang; Munguba, Gustavo C et al. (2008) Corepressor CtBP and nuclear speckle protein Pnn/DRS differentially modulate transcription and splicing of the E-cadherin gene. Mol Cell Biol 28:1584-95
Joo, Jeong-Hoon; Lee, Young Jae; Munguba, Gustavo C et al. (2007) Role of Pinin in neural crest, dorsal dermis, and axial skeleton development and its involvement in the regulation of Tcf/Lef activity in mice. Dev Dyn 236:2147-58
Joo, Jeong-Hoon; Alpatov, Roman; Munguba, Gustavo C et al. (2005) Reduction of Pnn by RNAi induces loss of cell-cell adhesion between human corneal epithelial cells. Mol Vis 11:133-42
Alpatov, Roman; Munguba, Gustavo Costa; Caton, Paul et al. (2004) Nuclear speckle-associated protein Pnn/DRS binds to the transcriptional corepressor CtBP and relieves CtBP-mediated repression of the E-cadherin gene. Mol Cell Biol 24:10223-35

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