Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY009349-04
Application #
2162963
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1993-01-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1997-12-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Tufts University
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02111
Chen, Wei-Sheng; Cao, Zhiyi; Leffler, Hakon et al. (2017) Galectin-3 Inhibition by a Small-Molecule Inhibitor Reduces Both Pathological Corneal Neovascularization and Fibrosis. Invest Ophthalmol Vis Sci 58:9-20
Sampson, James F; Suryawanshi, Amol; Chen, Wei-Sheng et al. (2016) Galectin-8 promotes regulatory T-cell differentiation by modulating IL-2 and TGF? signaling. Immunol Cell Biol 94:213-9
Chen, Wei-Sheng; Cao, Zhiyi; Sugaya, Satoshi et al. (2016) Pathological lymphangiogenesis is modulated by galectin-8-dependent crosstalk between podoplanin and integrin-associated VEGFR-3. Nat Commun 7:11302
Sampson, James F; Hasegawa, Eiichi; Mulki, Lama et al. (2015) Galectin-8 Ameliorates Murine Autoimmune Ocular Pathology and Promotes a Regulatory T Cell Response. PLoS One 10:e0130772
Chen, Wei-Sheng; Cao, Zhiyi; Truong, Laetitia et al. (2015) Fingerprinting of galectins in normal, P. aeruginosa-infected, and chemically burned mouse corneas. Invest Ophthalmol Vis Sci 56:515-25
Suryawanshi, Amol; Cao, Zhiyi; Sampson, James F et al. (2015) IL-17A-mediated protection against Acanthamoeba keratitis. J Immunol 194:650-63
Cao, Zhiyi; Saravanan, Chandrassegar; Chen, Wei-Sheng et al. (2015) Examination of the role of galectins in cell migration and re-epithelialization of wounds. Methods Mol Biol 1207:317-26
Sugaya, Satoshi; Chen, Wei-Sheng; Cao, Zhiyi et al. (2015) Comparison of galectin expression signatures in rejected and accepted murine corneal allografts. Cornea 34:675-681
Markowska, Anna I; Cao, Zhiyi; Panjwani, Noorjahan (2014) Glycobiology of ocular angiogenesis. Glycobiology 24:1275-82
Suryawanshi, Amol; Cao, Zhiyi; Thitiprasert, Thananya et al. (2013) Galectin-1-mediated suppression of Pseudomonas aeruginosa-induced corneal immunopathology. J Immunol 190:6397-409

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