Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY010577-04
Application #
2164550
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1993-08-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Thomas Jefferson University
Department
Pathology
Type
Schools of Medicine
DUNS #
061197161
City
Philadelphia
State
PA
Country
United States
Zip Code
19107
Klionsky, Daniel J (see original citation for additional authors) (2016) Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12:1-222
Basu, Subhasree; Rajakaruna, Suren; De Arcangelis, Adèle et al. (2014) ?6 integrin transactivates insulin-like growth factor receptor-1 (IGF-1R) to regulate caspase-3-mediated lens epithelial cell differentiation initiation. J Biol Chem 289:3842-55
Basu, Subhasree; Rajakaruna, Suren; Dickinson, Bryan C et al. (2014) Endogenous hydrogen peroxide production in the epithelium of the developing embryonic lens. Mol Vis 20:458-67
Basu, Subhasree; Rajakaruna, Suren; Reyes, Beverly et al. (2014) Suppression of MAPK/JNK-MTORC1 signaling leads to premature loss of organelles and nuclei by autophagy during terminal differentiation of lens fiber cells. Autophagy 10:1193-211
Chauss, Daniel; Basu, Subhasree; Rajakaruna, Suren et al. (2014) Differentiation state-specific mitochondrial dynamic regulatory networks are revealed by global transcriptional analysis of the developing chicken lens. G3 (Bethesda) 4:1515-27
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Basu, Subhasree; Rajakaruna, Suren; Menko, A Sue (2012) Insulin-like growth factor receptor-1 and nuclear factor ?B are crucial survival signals that regulate caspase-3-mediated lens epithelial cell differentiation initiation. J Biol Chem 287:8384-97
Leonard, Michelle; Zhang, Liping; Zhai, Ni et al. (2011) Modulation of N-cadherin junctions and their role as epicenters of differentiation-specific actin regulation in the developing lens. Dev Biol 349:363-77
Menko, A Sue; Andley, Usha P (2010) ?A-Crystallin associates with ?6 integrin receptor complexes and regulates cellular signaling. Exp Eye Res 91:640-51

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