Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM024797-19
Application #
2174331
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1978-01-01
Project End
1998-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
19
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Radiation-Diagnostic/Oncology
Type
Organized Research Units
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Smith, Jeffrey B; Herschman, Harvey R (2004) Targeted identification of glucocorticoid-attenuated response genes: in vitro and in vivo models. Proc Am Thorac Soc 1:275-81
Smith, J J; Rucknagel, K P; Schierhorn, A et al. (1999) Unusual sites of arginine methylation in Poly(A)-binding protein II and in vitro methylation by protein arginine methyltransferases PRMT1 and PRMT3. J Biol Chem 274:13229-34
Huang, M; Stolina, M; Sharma, S et al. (1998) Non-small cell lung cancer cyclooxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages: up-regulation of interleukin 10 and down-regulation of interleukin 12 production. Cancer Res 58:1208-16
Rovai, L E; Herschman, H R; Smith, J B (1998) The murine neutrophil-chemoattractant chemokines LIX, KC, and MIP-2 have distinct induction kinetics, tissue distributions, and tissue-specific sensitivities to glucocorticoid regulation in endotoxemia. J Leukoc Biol 64:494-502
Tang, J; Gary, J D; Clarke, S et al. (1998) PRMT 3, a type I protein arginine N-methyltransferase that differs from PRMT1 in its oligomerization, subcellular localization, substrate specificity, and regulation. J Biol Chem 273:16935-45
Tetradis, S; Pilbeam, C C; Liu, Y et al. (1997) Parathyroid hormone increases prostaglandin G/H synthase-2 transcription by a cyclic adenosine 3',5'-monophosphate-mediated pathway in murine osteoblastic MC3T3-E1 cells. Endocrinology 138:3594-600
Smith, J B; Rovai, L E; Herschman, H R (1997) Sequence similarities of a subgroup of CXC chemokines related to murine LIX: implications for the interpretation of evolutionary relationships among chemokines. J Leukoc Biol 62:598-603
Rovai, L E; Herschman, H R; Smith, J B (1997) Cloning and characterization of the human granulocyte chemotactic protein-2 gene. J Immunol 158:5257-66
Smith, J B; Herschman, H R (1997) Identification of inflammatory mediators by screening for glucocorticoid-attenuated response genes. Methods Enzymol 287:250-65
Xie, W; Herschman, H R (1996) Transcriptional regulation of prostaglandin synthase 2 gene expression by platelet-derived growth factor and serum. J Biol Chem 271:31742-8

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