Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM028835-12S1
Application #
3276168
Study Section
Physical Biochemistry Study Section (PB)
Project Start
1980-08-01
Project End
1994-06-30
Budget Start
1992-07-01
Budget End
1993-06-30
Support Year
12
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
City
Rochester
State
MN
Country
United States
Zip Code
55905
Strehler, Emanuel E (2013) Plasma membrane calcium ATPases as novel candidates for therapeutic agent development. J Pharm Pharm Sci 16:190-206
Caride, Ariel J; Bennett, Richard D; Strehler, Emanuel E (2010) Kinetic analysis reveals differences in the binding mechanism of calmodulin and calmodulin-like protein to the IQ motifs of myosin-10. Biochemistry 49:8105-16
Bajzer, Zeljko; Huzak, Miljenko; Neff, Kevin L et al. (2008) Mathematical analysis of models for reaction kinetics in intracellular environments. Math Biosci 215:35-47
Caride, Ariel J; Filoteo, Adelaida G; Penniston, John T et al. (2007) The plasma membrane Ca2+ pump isoform 4a differs from isoform 4b in the mechanism of calmodulin binding and activation kinetics: implications for Ca2+ signaling. J Biol Chem 282:25640-8
Ribiczey, Polett; Tordai, Attila; Andrikovics, Hajnalka et al. (2007) Isoform-specific up-regulation of plasma membrane Ca2+ATPase expression during colon and gastric cancer cell differentiation. Cell Calcium 42:590-605
Strehler, E E; Filoteo, A G; Penniston, J T et al. (2007) Plasma-membrane Ca(2+) pumps: structural diversity as the basis for functional versatility. Biochem Soc Trans 35:919-22
Vanagas, Laura; Rossi, Rolando C; Caride, Ariel J et al. (2007) Plasma membrane calcium pump activity is affected by the membrane protein concentration: evidence for the involvement of the actin cytoskeleton. Biochim Biophys Acta 1768:1641-9
Paszty, Katalin; Antalffy, Geza; Hegedus, Luca et al. (2007) Cleavage of the plasma membrane Ca+ATPase during apoptosis. Ann N Y Acad Sci 1099:440-50
Strehler, Emanuel E; Caride, Ariel J; Filoteo, Adelaida G et al. (2007) Plasma membrane Ca2+ ATPases as dynamic regulators of cellular calcium handling. Ann N Y Acad Sci 1099:226-36
Kip, Sertac N; Strehler, Emanuel E (2007) Rapid downregulation of NCX and PMCA in hippocampal neurons following H2O2 oxidative stress. Ann N Y Acad Sci 1099:436-9

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